caa a22 4500 605536600 CHVBK 20210128100853.0 cr unu---uuuuu 210128e20150601xx s 000 0 eng 10.1007/s10517-015-2936-3 doi (NATIONALLICENCE)springer-10.1007/s10517-015-2936-3 Cell-Mediated Hemolytic Activity of Nosocomial Pseudomonas Aeruginosa Strains [Elektronische Daten] [M. Kuznetsova, T. Karpunina] Cell-mediated hemolysis and adhesion index of nosocomial P. aeruginosa strains were experimentally studied. The highest hemoglobin release was recorded after centrifugation of erythrocyte and bacterial cell suspension preincubated at 37C. All cultures were referred to highly adherent variants. The relationship between P. aeruginosa adhesion activity and erythrocyte lysis was found only in "passive” cell-cell contact. No correlation between cellassociated hemolysis and hemolysis caused by secreted factors was detected. It seems that the cytotoxicity of the studied P. aeruginosa strains was determined by ExoU and ExoS third type secretion effectors. Springer Science+Business Media New York, 2015 P. aeruginosa nationallicence cell-mediated hemolysis nationallicence adhesion nationallicence ExoU nationallicence ExoS nationallicence Kuznetsova M. Institute of Ecology and Genetics of Microorganisms, Ural Division of the Russian Academy of Sciences, Perm, Russia aut Karpunina T. E. A. Wagner Perm State Medical Academy, Ministry of Health of the Russian Federation, Perm, Russia aut Bulletin of Experimental Biology and Medicine Springer US; http://www.springer-ny.com 159/2(2015-06-01), 258-261 0007-4888 159:2<258 2015 159 10517 https://doi.org/10.1007/s10517-015-2936-3 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s10517-015-2936-3 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Kuznetsova M. Institute of Ecology and Genetics of Microorganisms, Ural Division of the Russian Academy of Sciences, Perm, Russia aut NATIONALLICENCE 700 1- Karpunina T. E. A. Wagner Perm State Medical Academy, Ministry of Health of the Russian Federation, Perm, Russia aut NATIONALLICENCE 773 0- Bulletin of Experimental Biology and Medicine Springer US; http://www.springer-ny.com 159/2(2015-06-01), 258-261 0007-4888 159:2<258 2015 159 10517