Effects of a Preparation Containing Pantogam, Succinic Acid, and Chitosan on Activities of the Glutathione System and NADPH-Generating Enzymes in Rat Tissues under Conditions of Cerebral Ischemia/Reperfusion
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| 024 | 7 | 0 | |a 10.1007/s10517-015-2927-4 |2 doi |
| 035 | |a (NATIONALLICENCE)springer-10.1007/s10517-015-2927-4 | ||
| 245 | 0 | 0 | |a Effects of a Preparation Containing Pantogam, Succinic Acid, and Chitosan on Activities of the Glutathione System and NADPH-Generating Enzymes in Rat Tissues under Conditions of Cerebral Ischemia/Reperfusion |h [Elektronische Daten] |c [O. Safonova, T. Popova, A. Slivkin, Yu. Talmi] |
| 520 | 3 | |a Treatment with the complex preparation containing pantogam, succinic acid, and chitosan normalized the concentration of reduced glutathione and activities of glutathione peroxidase, glutathione reductase, and some NADPH-generating enzymes (glucose-6-phosphate dehydrogenase and NADPH-isocitrate dehydrogenase) in animals with experimental hypoxia/reperfusion of the brain. These results can be explained by suppression of free radical oxidation and normalization of the antioxidant system related to the neuroprotective, antihypoxic, and antioxidant properties of these substances, their involvement into the regulation of cell metabolism under pathological conditions accompanied by oxidative stress. | |
| 540 | |a Springer Science+Business Media New York, 2015 | ||
| 690 | 7 | |a pantogam |2 nationallicence | |
| 690 | 7 | |a succinic acid |2 nationallicence | |
| 690 | 7 | |a chitosan |2 nationallicence | |
| 690 | 7 | |a brain ischemia/reperfusion |2 nationallicence | |
| 690 | 7 | |a glutathione antioxidant system |2 nationallicence | |
| 700 | 1 | |a Safonova |D O. |u Voronezh State University, Voronezh, Russia |4 aut | |
| 700 | 1 | |a Popova |D T. |u Voronezh State University, Voronezh, Russia |4 aut | |
| 700 | 1 | |a Slivkin |D A. |u Voronezh State University, Voronezh, Russia |4 aut | |
| 700 | 1 | |a Talmi |D Yu |u Voronezh State University, Voronezh, Russia |4 aut | |
| 773 | 0 | |t Bulletin of Experimental Biology and Medicine |d Springer US; http://www.springer-ny.com |g 159/2(2015-06-01), 221-224 |x 0007-4888 |q 159:2<221 |1 2015 |2 159 |o 10517 | |
| 856 | 4 | 0 | |u https://doi.org/10.1007/s10517-015-2927-4 |q text/html |z Onlinezugriff via DOI |
| 898 | |a BK010053 |b XK010053 |c XK010000 | ||
| 900 | 7 | |a Metadata rights reserved |b Springer special CC-BY-NC licence |2 nationallicence | |
| 908 | |D 1 |a research-article |2 jats | ||
| 949 | |B NATIONALLICENCE |F NATIONALLICENCE |b NL-springer | ||
| 950 | |B NATIONALLICENCE |P 856 |E 40 |u https://doi.org/10.1007/s10517-015-2927-4 |q text/html |z Onlinezugriff via DOI | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Safonova |D O. |u Voronezh State University, Voronezh, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Popova |D T. |u Voronezh State University, Voronezh, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Slivkin |D A. |u Voronezh State University, Voronezh, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Talmi |D Yu |u Voronezh State University, Voronezh, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 773 |E 0- |t Bulletin of Experimental Biology and Medicine |d Springer US; http://www.springer-ny.com |g 159/2(2015-06-01), 221-224 |x 0007-4888 |q 159:2<221 |1 2015 |2 159 |o 10517 | ||