caa a22 4500 605536643 CHVBK 20210128100853.0 cr unu---uuuuu 210128e20150601xx s 000 0 eng 10.1007/s10517-015-2934-5 doi (NATIONALLICENCE)springer-10.1007/s10517-015-2934-5 Expression of Pattern Recognition Receptors by Nociceptive Metasympathetic Neurons [Elektronische Daten] [L. Filippova, E. Bystrova, F. Malyshev, O. Platonova, A. Nozdrachev] Immunohistochemical assay with double label and confocal laser scanning microscopy showed that innate immunity receptor TLR4 is expressed predominantly in neurons of the intestinal Auerbach (myenteric) plexus, while vanilloid nociceptive receptor TRPV1 is expressed by neurons of Meissner (submucous) plexus. Immunohistochemical analysis with triple labeling revealed coexpression of TLR4 and TRPV1 in enteric neurons of rat colon. The results attest to a possibility of functional interaction between Toll-like and vanilloid receptors in the neuron level. Springer Science+Business Media New York, 2015 intestine nationallicence neuron nationallicence TLR4 nationallicence TRPV1 nationallicence coexpression nationallicence Filippova L. I. P. Pavlov Institute of Physiology, Russian Academy of Medical Sciences, St. Petersburg, Russia aut Bystrova E. I. P. Pavlov Institute of Physiology, Russian Academy of Medical Sciences, St. Petersburg, Russia aut Malyshev F. I. P. Pavlov Institute of Physiology, Russian Academy of Medical Sciences, St. Petersburg, Russia aut Platonova O. I. P. Pavlov Institute of Physiology, Russian Academy of Medical Sciences, St. Petersburg, Russia aut Nozdrachev A. I. P. Pavlov Institute of Physiology, Russian Academy of Medical Sciences, St. Petersburg, Russia aut Bulletin of Experimental Biology and Medicine Springer US; http://www.springer-ny.com 159/2(2015-06-01), 248-252 0007-4888 159:2<248 2015 159 10517 https://doi.org/10.1007/s10517-015-2934-5 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s10517-015-2934-5 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Filippova L. I. P. Pavlov Institute of Physiology, Russian Academy of Medical Sciences, St. Petersburg, Russia aut NATIONALLICENCE 700 1- Bystrova E. I. P. Pavlov Institute of Physiology, Russian Academy of Medical Sciences, St. Petersburg, Russia aut NATIONALLICENCE 700 1- Malyshev F. I. P. Pavlov Institute of Physiology, Russian Academy of Medical Sciences, St. Petersburg, Russia aut NATIONALLICENCE 700 1- Platonova O. I. P. Pavlov Institute of Physiology, Russian Academy of Medical Sciences, St. Petersburg, Russia aut NATIONALLICENCE 700 1- Nozdrachev A. I. P. Pavlov Institute of Physiology, Russian Academy of Medical Sciences, St. Petersburg, Russia aut NATIONALLICENCE 773 0- Bulletin of Experimental Biology and Medicine Springer US; http://www.springer-ny.com 159/2(2015-06-01), 248-252 0007-4888 159:2<248 2015 159 10517