Metabolic Abnormalities in Erythrocyte Membranes and Liver Tissue Homogenates in Experimental Diabetes Mellitus
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| 024 | 7 | 0 | |a 10.1007/s10517-015-2921-x |2 doi |
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| 245 | 0 | 0 | |a Metabolic Abnormalities in Erythrocyte Membranes and Liver Tissue Homogenates in Experimental Diabetes Mellitus |h [Elektronische Daten] |c [N. Mikaelyan, H. Nguen, A. Terent'ev] |
| 520 | 3 | |a Considerable changes in serum lipids and lipoprotein profiles associated with hypertriglyceridemia, hypercholesterolemia, increased VLDL and LDL concentrations, and reduced HDL level occur at the early stages of streptozotocin-induced diabetes (day 7) in rats. The level of saturated palmitic fatty acid increased and the levels of monounsaturated fatty acids decreased at the expense of oleic acid, which considerably differed from changes in these parameters observed in patients with diabetes mellitus. Our fi ndings suggest that changes in the lipid composition and fatty acid pool in erythrocytes and liver homogenates are pro-atherosclerotic already in the early stages of diabetes development. | |
| 540 | |a Springer Science+Business Media New York, 2015 | ||
| 690 | 7 | |a diabetes mellitus |2 nationallicence | |
| 690 | 7 | |a fatty acids |2 nationallicence | |
| 690 | 7 | |a atherosclerosis |2 nationallicence | |
| 690 | 7 | |a liver homogenates |2 nationallicence | |
| 700 | 1 | |a Mikaelyan |D N. |u N. I. Pirogov Russian National Research Medical University, Ministry of Health of the Russian Federation, Moscow, Russia |4 aut | |
| 700 | 1 | |a Nguen |D H. |u N. I. Pirogov Russian National Research Medical University, Ministry of Health of the Russian Federation, Moscow, Russia |4 aut | |
| 700 | 1 | |a Terent'ev |D A. |u N. I. Pirogov Russian National Research Medical University, Ministry of Health of the Russian Federation, Moscow, Russia |4 aut | |
| 773 | 0 | |t Bulletin of Experimental Biology and Medicine |d Springer US; http://www.springer-ny.com |g 159/2(2015-06-01), 197-200 |x 0007-4888 |q 159:2<197 |1 2015 |2 159 |o 10517 | |
| 856 | 4 | 0 | |u https://doi.org/10.1007/s10517-015-2921-x |q text/html |z Onlinezugriff via DOI |
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| 900 | 7 | |a Metadata rights reserved |b Springer special CC-BY-NC licence |2 nationallicence | |
| 908 | |D 1 |a research-article |2 jats | ||
| 949 | |B NATIONALLICENCE |F NATIONALLICENCE |b NL-springer | ||
| 950 | |B NATIONALLICENCE |P 856 |E 40 |u https://doi.org/10.1007/s10517-015-2921-x |q text/html |z Onlinezugriff via DOI | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Mikaelyan |D N. |u N. I. Pirogov Russian National Research Medical University, Ministry of Health of the Russian Federation, Moscow, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Nguen |D H. |u N. I. Pirogov Russian National Research Medical University, Ministry of Health of the Russian Federation, Moscow, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Terent'ev |D A. |u N. I. Pirogov Russian National Research Medical University, Ministry of Health of the Russian Federation, Moscow, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 773 |E 0- |t Bulletin of Experimental Biology and Medicine |d Springer US; http://www.springer-ny.com |g 159/2(2015-06-01), 197-200 |x 0007-4888 |q 159:2<197 |1 2015 |2 159 |o 10517 | ||