caa a22 4500 605536651 CHVBK 20210128100853.0 cr unu---uuuuu 210128e20150601xx s 000 0 eng 10.1007/s10517-015-2921-x doi (NATIONALLICENCE)springer-10.1007/s10517-015-2921-x Metabolic Abnormalities in Erythrocyte Membranes and Liver Tissue Homogenates in Experimental Diabetes Mellitus [Elektronische Daten] [N. Mikaelyan, H. Nguen, A. Terent'ev] Considerable changes in serum lipids and lipoprotein profiles associated with hypertriglyceridemia, hypercholesterolemia, increased VLDL and LDL concentrations, and reduced HDL level occur at the early stages of streptozotocin-induced diabetes (day 7) in rats. The level of saturated palmitic fatty acid increased and the levels of monounsaturated fatty acids decreased at the expense of oleic acid, which considerably differed from changes in these parameters observed in patients with diabetes mellitus. Our fi ndings suggest that changes in the lipid composition and fatty acid pool in erythrocytes and liver homogenates are pro-atherosclerotic already in the early stages of diabetes development. Springer Science+Business Media New York, 2015 diabetes mellitus nationallicence fatty acids nationallicence atherosclerosis nationallicence liver homogenates nationallicence Mikaelyan N. N. I. Pirogov Russian National Research Medical University, Ministry of Health of the Russian Federation, Moscow, Russia aut Nguen H. N. I. Pirogov Russian National Research Medical University, Ministry of Health of the Russian Federation, Moscow, Russia aut Terent'ev A. N. I. Pirogov Russian National Research Medical University, Ministry of Health of the Russian Federation, Moscow, Russia aut Bulletin of Experimental Biology and Medicine Springer US; http://www.springer-ny.com 159/2(2015-06-01), 197-200 0007-4888 159:2<197 2015 159 10517 https://doi.org/10.1007/s10517-015-2921-x text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s10517-015-2921-x text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Mikaelyan N. N. I. Pirogov Russian National Research Medical University, Ministry of Health of the Russian Federation, Moscow, Russia aut NATIONALLICENCE 700 1- Nguen H. N. I. Pirogov Russian National Research Medical University, Ministry of Health of the Russian Federation, Moscow, Russia aut NATIONALLICENCE 700 1- Terent'ev A. N. I. Pirogov Russian National Research Medical University, Ministry of Health of the Russian Federation, Moscow, Russia aut NATIONALLICENCE 773 0- Bulletin of Experimental Biology and Medicine Springer US; http://www.springer-ny.com 159/2(2015-06-01), 197-200 0007-4888 159:2<197 2015 159 10517