Factors of Th17 and Treg Lymphocyte Differentiation in Pulmonary Tuberculosis
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| 024 | 7 | 0 | |a 10.1007/s10517-015-2922-9 |2 doi |
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| 245 | 0 | 0 | |a Factors of Th17 and Treg Lymphocyte Differentiation in Pulmonary Tuberculosis |h [Elektronische Daten] |c [T. Kononova, O. Urazova, V. Novitskii, Yu. Kolobovnikova, E. Churina, P. Zakharova] |
| 520 | 3 | |a In patients with infiltrative pulmonary tuberculosis, the increase in IL-6 secretion, the decrease in TGFβ production (in case of drug resistance of the causative agent), and unchanged level of IL-1β secretion by mononuclear leukocytes in vitro were associated with increased number of CD4+CD161+IL-17A+ Th17 lymphocytes in the peripheral blood. In patients with disseminated drug-resistant pulmonary tuberculosis, TGFβ hyperproduction promoted differentiation of CD4+CD25+FoxP3+ Treg lymphocytes with immunosuppressive activity. | |
| 540 | |a Springer Science+Business Media New York, 2015 | ||
| 690 | 7 | |a Th17 lymphocytes |2 nationallicence | |
| 690 | 7 | |a Treg lymphocytes |2 nationallicence | |
| 690 | 7 | |a cytokines |2 nationallicence | |
| 690 | 7 | |a pulmonary tuberculosis |2 nationallicence | |
| 700 | 1 | |a Kononova |D T. |u Department of Pathophysiology, Siberian State Medical University, Ministry of Health of the Russian Federation, Tomsk, Russia |4 aut | |
| 700 | 1 | |a Urazova |D O. |u Department of Pathophysiology, Siberian State Medical University, Ministry of Health of the Russian Federation, Tomsk, Russia |4 aut | |
| 700 | 1 | |a Novitskii |D V. |u Department of Pathophysiology, Siberian State Medical University, Ministry of Health of the Russian Federation, Tomsk, Russia |4 aut | |
| 700 | 1 | |a Kolobovnikova |D Yu |u Department of Pathophysiology, Siberian State Medical University, Ministry of Health of the Russian Federation, Tomsk, Russia |4 aut | |
| 700 | 1 | |a Churina |D E. |u Department of Pathophysiology, Siberian State Medical University, Ministry of Health of the Russian Federation, Tomsk, Russia |4 aut | |
| 700 | 1 | |a Zakharova |D P. |u Department of Pathophysiology, Siberian State Medical University, Ministry of Health of the Russian Federation, Tomsk, Russia |4 aut | |
| 773 | 0 | |t Bulletin of Experimental Biology and Medicine |d Springer US; http://www.springer-ny.com |g 159/2(2015-06-01), 201-204 |x 0007-4888 |q 159:2<201 |1 2015 |2 159 |o 10517 | |
| 856 | 4 | 0 | |u https://doi.org/10.1007/s10517-015-2922-9 |q text/html |z Onlinezugriff via DOI |
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| 908 | |D 1 |a research-article |2 jats | ||
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| 950 | |B NATIONALLICENCE |P 856 |E 40 |u https://doi.org/10.1007/s10517-015-2922-9 |q text/html |z Onlinezugriff via DOI | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Kononova |D T. |u Department of Pathophysiology, Siberian State Medical University, Ministry of Health of the Russian Federation, Tomsk, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Urazova |D O. |u Department of Pathophysiology, Siberian State Medical University, Ministry of Health of the Russian Federation, Tomsk, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Novitskii |D V. |u Department of Pathophysiology, Siberian State Medical University, Ministry of Health of the Russian Federation, Tomsk, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Kolobovnikova |D Yu |u Department of Pathophysiology, Siberian State Medical University, Ministry of Health of the Russian Federation, Tomsk, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Churina |D E. |u Department of Pathophysiology, Siberian State Medical University, Ministry of Health of the Russian Federation, Tomsk, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Zakharova |D P. |u Department of Pathophysiology, Siberian State Medical University, Ministry of Health of the Russian Federation, Tomsk, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 773 |E 0- |t Bulletin of Experimental Biology and Medicine |d Springer US; http://www.springer-ny.com |g 159/2(2015-06-01), 201-204 |x 0007-4888 |q 159:2<201 |1 2015 |2 159 |o 10517 | ||