Role of JNK and Involvement of p53 in Stimulation of Growth Potential Realization of Mesenchymal Precursor Cells by Alkaloid Songorine
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| 024 | 7 | 0 | |a 10.1007/s10517-015-3099-y |2 doi |
| 035 | |a (NATIONALLICENCE)springer-10.1007/s10517-015-3099-y | ||
| 245 | 0 | 0 | |a Role of JNK and Involvement of p53 in Stimulation of Growth Potential Realization of Mesenchymal Precursor Cells by Alkaloid Songorine |h [Elektronische Daten] |c [G. Zyuz'kov, V. Zhdanov, E. Udut, L. Miroshnichenko, A. Chaikovskii, E. Simanina, V. Udut, L. Stavrova, T. Polyakova, M. Minakova, O. Trifonova, T. Gridneva, A. Dygai] |
| 520 | 3 | |a The role of JNK-mediated signal pathway and participation of p53 transcription factor in stimulation of realization of the growth potential of the mesenchymal precursor cells by alkaloid songorine were examined in vitro. Specific inhibitors of JNK and p53 enhanced stimulation of fibroblast colony/cluster formation and proliferative activity of mesenchymal precursor cells. Under these conditions, more pronounced effects were observed with early precursors of fibroblast CFU and in both cases were accompanied by a decrease in differentiation index of progenitor elements. | |
| 540 | |a Springer Science+Business Media New York, 2015 | ||
| 690 | 7 | |a JNK |2 nationallicence | |
| 690 | 7 | |a p53 |2 nationallicence | |
| 690 | 7 | |a alkaloids |2 nationallicence | |
| 690 | 7 | |a stem cells |2 nationallicence | |
| 690 | 7 | |a regenerative medicine |2 nationallicence | |
| 700 | 1 | |a Zyuz'kov |D G. |u E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk, Russia |4 aut | |
| 700 | 1 | |a Zhdanov |D V. |u E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk, Russia |4 aut | |
| 700 | 1 | |a Udut |D E. |u E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk, Russia |4 aut | |
| 700 | 1 | |a Miroshnichenko |D L. |u E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk, Russia |4 aut | |
| 700 | 1 | |a Chaikovskii |D A. |u E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk, Russia |4 aut | |
| 700 | 1 | |a Simanina |D E. |u E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk, Russia |4 aut | |
| 700 | 1 | |a Udut |D V. |u E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk, Russia |4 aut | |
| 700 | 1 | |a Stavrova |D L. |u E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk, Russia |4 aut | |
| 700 | 1 | |a Polyakova |D T. |u E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk, Russia |4 aut | |
| 700 | 1 | |a Minakova |D M. |u E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk, Russia |4 aut | |
| 700 | 1 | |a Trifonova |D O. |u E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk, Russia |4 aut | |
| 700 | 1 | |a Gridneva |D T. |u E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk, Russia |4 aut | |
| 700 | 1 | |a Dygai |D A. |u E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk, Russia |4 aut | |
| 773 | 0 | |t Bulletin of Experimental Biology and Medicine |d Springer US; http://www.springer-ny.com |g 160/1(2015-11-01), 64-67 |x 0007-4888 |q 160:1<64 |1 2015 |2 160 |o 10517 | |
| 856 | 4 | 0 | |u https://doi.org/10.1007/s10517-015-3099-y |q text/html |z Onlinezugriff via DOI |
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| 900 | 7 | |a Metadata rights reserved |b Springer special CC-BY-NC licence |2 nationallicence | |
| 908 | |D 1 |a research-article |2 jats | ||
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| 950 | |B NATIONALLICENCE |P 856 |E 40 |u https://doi.org/10.1007/s10517-015-3099-y |q text/html |z Onlinezugriff via DOI | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Zyuz'kov |D G. |u E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Zhdanov |D V. |u E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Udut |D E. |u E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Miroshnichenko |D L. |u E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Chaikovskii |D A. |u E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Simanina |D E. |u E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Udut |D V. |u E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Stavrova |D L. |u E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Polyakova |D T. |u E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Minakova |D M. |u E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Trifonova |D O. |u E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Gridneva |D T. |u E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Dygai |D A. |u E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 773 |E 0- |t Bulletin of Experimental Biology and Medicine |d Springer US; http://www.springer-ny.com |g 160/1(2015-11-01), 64-67 |x 0007-4888 |q 160:1<64 |1 2015 |2 160 |o 10517 | ||