Effect of Paclitaxel on Antitumor Activity of Cyclophosphamide: Study on Two Transplanted Tumors in Mice

Verfasser / Beitragende:
[V. Kaledin, V. Nikolin, N. Popova, I. Pyshnaya, L. Bogdanova, T. Morozkova]
Ort, Verlag, Jahr:
2015
Enthalten in:
Bulletin of Experimental Biology and Medicine, 160/1(2015-11-01), 81-83
Format:
Artikel (online)
ID: 605536813
LEADER caa a22 4500
001 605536813
003 CHVBK
005 20210128100854.0
007 cr unu---uuuuu
008 210128e20151101xx s 000 0 eng
024 7 0 |a 10.1007/s10517-015-3103-6  |2 doi 
035 |a (NATIONALLICENCE)springer-10.1007/s10517-015-3103-6 
245 0 0 |a Effect of Paclitaxel on Antitumor Activity of Cyclophosphamide: Study on Two Transplanted Tumors in Mice  |h [Elektronische Daten]  |c [V. Kaledin, V. Nikolin, N. Popova, I. Pyshnaya, L. Bogdanova, T. Morozkova] 
520 3 |a Antitumor effect of paclitaxel used as the monotherapy or in combination with cyclophosphamide was studied on CBA/LacSto mice with transplanted LS and RLS tumors characterized by high (LS) and low (RLS) sensitivity to cyclophosphamide. The therapeutic effects of cyclophosphamide and paclitaxel were summed in animals with drug-resistant RLS tumor, while combined use of these drugs in LS tumor highly sensitive to the apoptogenic effect of cyclophosphamide was no more effective than cyclophosphamide alone. 
540 |a Springer Science+Business Media New York, 2015 
690 7 |a malignant tumors  |2 nationallicence 
690 7 |a cyclophosphamide  |2 nationallicence 
690 7 |a paclitaxel  |2 nationallicence 
690 7 |a apoptosis  |2 nationallicence 
700 1 |a Kaledin  |D V.  |u Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences, Novosibirsk, Russia  |4 aut 
700 1 |a Nikolin  |D V.  |u Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences, Novosibirsk, Russia  |4 aut 
700 1 |a Popova  |D N.  |u Novosibirsk State University, Novosibirsk, Russia  |4 aut 
700 1 |a Pyshnaya  |D I.  |u Institute of Chemical Biology and Basic Medicine, Siberian Division of the Russian Academy of Sciences, Novosibirsk, Russia  |4 aut 
700 1 |a Bogdanova  |D L.  |u Institute of Molecular Pathology and Pathomorphology, Novosibirsk, Russia  |4 aut 
700 1 |a Morozkova  |D T.  |u Institute of Molecular Pathology and Pathomorphology, Novosibirsk, Russia  |4 aut 
773 0 |t Bulletin of Experimental Biology and Medicine  |d Springer US; http://www.springer-ny.com  |g 160/1(2015-11-01), 81-83  |x 0007-4888  |q 160:1<81  |1 2015  |2 160  |o 10517 
856 4 0 |u https://doi.org/10.1007/s10517-015-3103-6  |q text/html  |z Onlinezugriff via DOI 
898 |a BK010053  |b XK010053  |c XK010000 
900 7 |a Metadata rights reserved  |b Springer special CC-BY-NC licence  |2 nationallicence 
908 |D 1  |a research-article  |2 jats 
949 |B NATIONALLICENCE  |F NATIONALLICENCE  |b NL-springer 
950 |B NATIONALLICENCE  |P 856  |E 40  |u https://doi.org/10.1007/s10517-015-3103-6  |q text/html  |z Onlinezugriff via DOI 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Kaledin  |D V.  |u Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences, Novosibirsk, Russia  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Nikolin  |D V.  |u Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences, Novosibirsk, Russia  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Popova  |D N.  |u Novosibirsk State University, Novosibirsk, Russia  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Pyshnaya  |D I.  |u Institute of Chemical Biology and Basic Medicine, Siberian Division of the Russian Academy of Sciences, Novosibirsk, Russia  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Bogdanova  |D L.  |u Institute of Molecular Pathology and Pathomorphology, Novosibirsk, Russia  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Morozkova  |D T.  |u Institute of Molecular Pathology and Pathomorphology, Novosibirsk, Russia  |4 aut 
950 |B NATIONALLICENCE  |P 773  |E 0-  |t Bulletin of Experimental Biology and Medicine  |d Springer US; http://www.springer-ny.com  |g 160/1(2015-11-01), 81-83  |x 0007-4888  |q 160:1<81  |1 2015  |2 160  |o 10517