caa a22 4500 605536813 CHVBK 20210128100854.0 cr unu---uuuuu 210128e20151101xx s 000 0 eng 10.1007/s10517-015-3103-6 doi (NATIONALLICENCE)springer-10.1007/s10517-015-3103-6 Effect of Paclitaxel on Antitumor Activity of Cyclophosphamide: Study on Two Transplanted Tumors in Mice [Elektronische Daten] [V. Kaledin, V. Nikolin, N. Popova, I. Pyshnaya, L. Bogdanova, T. Morozkova] Antitumor effect of paclitaxel used as the monotherapy or in combination with cyclophosphamide was studied on CBA/LacSto mice with transplanted LS and RLS tumors characterized by high (LS) and low (RLS) sensitivity to cyclophosphamide. The therapeutic effects of cyclophosphamide and paclitaxel were summed in animals with drug-resistant RLS tumor, while combined use of these drugs in LS tumor highly sensitive to the apoptogenic effect of cyclophosphamide was no more effective than cyclophosphamide alone. Springer Science+Business Media New York, 2015 malignant tumors nationallicence cyclophosphamide nationallicence paclitaxel nationallicence apoptosis nationallicence Kaledin V. Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences, Novosibirsk, Russia aut Nikolin V. Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences, Novosibirsk, Russia aut Popova N. Novosibirsk State University, Novosibirsk, Russia aut Pyshnaya I. Institute of Chemical Biology and Basic Medicine, Siberian Division of the Russian Academy of Sciences, Novosibirsk, Russia aut Bogdanova L. Institute of Molecular Pathology and Pathomorphology, Novosibirsk, Russia aut Morozkova T. Institute of Molecular Pathology and Pathomorphology, Novosibirsk, Russia aut Bulletin of Experimental Biology and Medicine Springer US; http://www.springer-ny.com 160/1(2015-11-01), 81-83 0007-4888 160:1<81 2015 160 10517 https://doi.org/10.1007/s10517-015-3103-6 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s10517-015-3103-6 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Kaledin V. Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences, Novosibirsk, Russia aut NATIONALLICENCE 700 1- Nikolin V. Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences, Novosibirsk, Russia aut NATIONALLICENCE 700 1- Popova N. Novosibirsk State University, Novosibirsk, Russia aut NATIONALLICENCE 700 1- Pyshnaya I. Institute of Chemical Biology and Basic Medicine, Siberian Division of the Russian Academy of Sciences, Novosibirsk, Russia aut NATIONALLICENCE 700 1- Bogdanova L. Institute of Molecular Pathology and Pathomorphology, Novosibirsk, Russia aut NATIONALLICENCE 700 1- Morozkova T. Institute of Molecular Pathology and Pathomorphology, Novosibirsk, Russia aut NATIONALLICENCE 773 0- Bulletin of Experimental Biology and Medicine Springer US; http://www.springer-ny.com 160/1(2015-11-01), 81-83 0007-4888 160:1<81 2015 160 10517