Pathomorphological Analysis and Evaluation of Microcirculation in Polyps of the External Urethral Meatus in Women

Verfasser / Beitragende:
[M. Bakarev, A. Neimark, E. Lushnikova, A. Pichigina, A. Yakovlev]
Ort, Verlag, Jahr:
2015
Enthalten in:
Bulletin of Experimental Biology and Medicine, 160/1(2015-11-01), 103-108
Format:
Artikel (online)
ID: 605536902
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024 7 0 |a 10.1007/s10517-015-3109-0  |2 doi 
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245 0 0 |a Pathomorphological Analysis and Evaluation of Microcirculation in Polyps of the External Urethral Meatus in Women  |h [Elektronische Daten]  |c [M. Bakarev, A. Neimark, E. Lushnikova, A. Pichigina, A. Yakovlev] 
520 3 |a Combinations of various factors of polypogenesis determine the formation of a mixed structural phenotype of urethral polyps consisting of heterogeneous changes of the epithelium (hyperplasia, metaplasia, and erosions), inflammatory cell infiltration of the stroma, and dilatation of the venous plexus vessels. Urogenital infections are associated with the predominance of symptoms of inflammation, high serum levels of IL-1β and TNF-α, more extensive areas of inflammatory infiltration and subepithelial microvascular bed, predominance of hyperemic form of microcirculatory disorders. The combination of hyperplastic reactions of the epithelial layer with neoangiogenesis and myofibroblast proliferation in the subepithelial zone confirms the key role of dysregeneratory hyperplasia in the mechanisms of polypogenesis. 
540 |a Springer Science+Business Media New York, 2015 
690 7 |a urethral polyp  |2 nationallicence 
690 7 |a urogenital infections  |2 nationallicence 
690 7 |a ureaplasma  |2 nationallicence 
690 7 |a pathomorphology  |2 nationallicence 
690 7 |a laser Doppler flowmetry  |2 nationallicence 
700 1 |a Bakarev  |D M.  |u Institute of Molecular Pathology and Pathomorphology, Novosibirsk, Russia  |4 aut 
700 1 |a Neimark  |D A.  |u Institute of Molecular Pathology and Pathomorphology, Novosibirsk, Russia  |4 aut 
700 1 |a Lushnikova  |D E.  |u Institute of Molecular Pathology and Pathomorphology, Novosibirsk, Russia  |4 aut 
700 1 |a Pichigina  |D A.  |u Institute of Molecular Pathology and Pathomorphology, Novosibirsk, Russia  |4 aut 
700 1 |a Yakovlev  |D A.  |u Institute of Molecular Pathology and Pathomorphology, Novosibirsk, Russia  |4 aut 
773 0 |t Bulletin of Experimental Biology and Medicine  |d Springer US; http://www.springer-ny.com  |g 160/1(2015-11-01), 103-108  |x 0007-4888  |q 160:1<103  |1 2015  |2 160  |o 10517 
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950 |B NATIONALLICENCE  |P 700  |E 1-  |a Bakarev  |D M.  |u Institute of Molecular Pathology and Pathomorphology, Novosibirsk, Russia  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Neimark  |D A.  |u Institute of Molecular Pathology and Pathomorphology, Novosibirsk, Russia  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Lushnikova  |D E.  |u Institute of Molecular Pathology and Pathomorphology, Novosibirsk, Russia  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Pichigina  |D A.  |u Institute of Molecular Pathology and Pathomorphology, Novosibirsk, Russia  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Yakovlev  |D A.  |u Institute of Molecular Pathology and Pathomorphology, Novosibirsk, Russia  |4 aut 
950 |B NATIONALLICENCE  |P 773  |E 0-  |t Bulletin of Experimental Biology and Medicine  |d Springer US; http://www.springer-ny.com  |g 160/1(2015-11-01), 103-108  |x 0007-4888  |q 160:1<103  |1 2015  |2 160  |o 10517