caa a22 4500 605536902 CHVBK 20210128100854.0 cr unu---uuuuu 210128e20151101xx s 000 0 eng 10.1007/s10517-015-3109-0 doi (NATIONALLICENCE)springer-10.1007/s10517-015-3109-0 Pathomorphological Analysis and Evaluation of Microcirculation in Polyps of the External Urethral Meatus in Women [Elektronische Daten] [M. Bakarev, A. Neimark, E. Lushnikova, A. Pichigina, A. Yakovlev] Combinations of various factors of polypogenesis determine the formation of a mixed structural phenotype of urethral polyps consisting of heterogeneous changes of the epithelium (hyperplasia, metaplasia, and erosions), inflammatory cell infiltration of the stroma, and dilatation of the venous plexus vessels. Urogenital infections are associated with the predominance of symptoms of inflammation, high serum levels of IL-1β and TNF-α, more extensive areas of inflammatory infiltration and subepithelial microvascular bed, predominance of hyperemic form of microcirculatory disorders. The combination of hyperplastic reactions of the epithelial layer with neoangiogenesis and myofibroblast proliferation in the subepithelial zone confirms the key role of dysregeneratory hyperplasia in the mechanisms of polypogenesis. Springer Science+Business Media New York, 2015 urethral polyp nationallicence urogenital infections nationallicence ureaplasma nationallicence pathomorphology nationallicence laser Doppler flowmetry nationallicence Bakarev M. Institute of Molecular Pathology and Pathomorphology, Novosibirsk, Russia aut Neimark A. Institute of Molecular Pathology and Pathomorphology, Novosibirsk, Russia aut Lushnikova E. Institute of Molecular Pathology and Pathomorphology, Novosibirsk, Russia aut Pichigina A. Institute of Molecular Pathology and Pathomorphology, Novosibirsk, Russia aut Yakovlev A. Institute of Molecular Pathology and Pathomorphology, Novosibirsk, Russia aut Bulletin of Experimental Biology and Medicine Springer US; http://www.springer-ny.com 160/1(2015-11-01), 103-108 0007-4888 160:1<103 2015 160 10517 https://doi.org/10.1007/s10517-015-3109-0 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s10517-015-3109-0 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Bakarev M. Institute of Molecular Pathology and Pathomorphology, Novosibirsk, Russia aut NATIONALLICENCE 700 1- Neimark A. Institute of Molecular Pathology and Pathomorphology, Novosibirsk, Russia aut NATIONALLICENCE 700 1- Lushnikova E. Institute of Molecular Pathology and Pathomorphology, Novosibirsk, Russia aut NATIONALLICENCE 700 1- Pichigina A. Institute of Molecular Pathology and Pathomorphology, Novosibirsk, Russia aut NATIONALLICENCE 700 1- Yakovlev A. Institute of Molecular Pathology and Pathomorphology, Novosibirsk, Russia aut NATIONALLICENCE 773 0- Bulletin of Experimental Biology and Medicine Springer US; http://www.springer-ny.com 160/1(2015-11-01), 103-108 0007-4888 160:1<103 2015 160 10517