Transsynaptic Coordination of the Formation of Morphofunctional Contacts between the Brain and the Neurotransplant: an Ulrastructural Study
Gespeichert in:
Verfasser / Beitragende:
[Z. Zhuravleva, G. Zhuravlev, E. Mugantseva]
Ort, Verlag, Jahr:
2015
Enthalten in:
Bulletin of Experimental Biology and Medicine, 160/1(2015-11-01), 91-95
Format:
Artikel (online)
Online Zugang:
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| 024 | 7 | 0 | |a 10.1007/s10517-015-3106-3 |2 doi |
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| 245 | 0 | 0 | |a Transsynaptic Coordination of the Formation of Morphofunctional Contacts between the Brain and the Neurotransplant: an Ulrastructural Study |h [Elektronische Daten] |c [Z. Zhuravleva, G. Zhuravlev, E. Mugantseva] |
| 520 | 3 | |a We studied the role of neurotransmitter signaling mediated by synaptic vesicles in the formation of aberrant functional connections between fascia dentata grafts and the somatosensory neocortex in adult rats. Quantitative analysis of the different populations of synaptic vesicles in the ectopic giant axonal endings of granular neurons was performed and the results were compared with the normal. Two pools of small clear vesicles (rapidly releasable pool and pool of reserve vesicles circulating in the active zone) and one pool of large dense-core vesicles were analyzed. Significant differences from the control suggest that synaptic integration of the transplants into the recipient brain is coordinated by transsynaptic signaling and mediated by different populations of synaptic vesicles. | |
| 540 | |a Springer Science+Business Media New York, 2015 | ||
| 690 | 7 | |a neurotransplant |2 nationallicence | |
| 690 | 7 | |a fascia dentata |2 nationallicence | |
| 690 | 7 | |a neocortex |2 nationallicence | |
| 690 | 7 | |a pool of the synaptic vesicles |2 nationallicence | |
| 690 | 7 | |a ultrastructure |2 nationallicence | |
| 700 | 1 | |a Zhuravleva |D Z. |u Institute of Theoretical and Experimental Biophysics, Russian Academy of Sciences, Pushchino, Moscow Region, Russia |4 aut | |
| 700 | 1 | |a Zhuravlev |D G. |u Institute of Cell Biophysics, Russian Academy of Science, Pushchino, Moscow Region, Russia |4 aut | |
| 700 | 1 | |a Mugantseva |D E. |u Institute of Theoretical and Experimental Biophysics, Russian Academy of Sciences, Pushchino, Moscow Region, Russia |4 aut | |
| 773 | 0 | |t Bulletin of Experimental Biology and Medicine |d Springer US; http://www.springer-ny.com |g 160/1(2015-11-01), 91-95 |x 0007-4888 |q 160:1<91 |1 2015 |2 160 |o 10517 | |
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| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Zhuravleva |D Z. |u Institute of Theoretical and Experimental Biophysics, Russian Academy of Sciences, Pushchino, Moscow Region, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Zhuravlev |D G. |u Institute of Cell Biophysics, Russian Academy of Science, Pushchino, Moscow Region, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Mugantseva |D E. |u Institute of Theoretical and Experimental Biophysics, Russian Academy of Sciences, Pushchino, Moscow Region, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 773 |E 0- |t Bulletin of Experimental Biology and Medicine |d Springer US; http://www.springer-ny.com |g 160/1(2015-11-01), 91-95 |x 0007-4888 |q 160:1<91 |1 2015 |2 160 |o 10517 | ||