Transsynaptic Coordination of the Formation of Morphofunctional Contacts between the Brain and the Neurotransplant: an Ulrastructural Study

Verfasser / Beitragende:
[Z. Zhuravleva, G. Zhuravlev, E. Mugantseva]
Ort, Verlag, Jahr:
2015
Enthalten in:
Bulletin of Experimental Biology and Medicine, 160/1(2015-11-01), 91-95
Format:
Artikel (online)
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024 7 0 |a 10.1007/s10517-015-3106-3  |2 doi 
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245 0 0 |a Transsynaptic Coordination of the Formation of Morphofunctional Contacts between the Brain and the Neurotransplant: an Ulrastructural Study  |h [Elektronische Daten]  |c [Z. Zhuravleva, G. Zhuravlev, E. Mugantseva] 
520 3 |a We studied the role of neurotransmitter signaling mediated by synaptic vesicles in the formation of aberrant functional connections between fascia dentata grafts and the somatosensory neocortex in adult rats. Quantitative analysis of the different populations of synaptic vesicles in the ectopic giant axonal endings of granular neurons was performed and the results were compared with the normal. Two pools of small clear vesicles (rapidly releasable pool and pool of reserve vesicles circulating in the active zone) and one pool of large dense-core vesicles were analyzed. Significant differences from the control suggest that synaptic integration of the transplants into the recipient brain is coordinated by transsynaptic signaling and mediated by different populations of synaptic vesicles. 
540 |a Springer Science+Business Media New York, 2015 
690 7 |a neurotransplant  |2 nationallicence 
690 7 |a fascia dentata  |2 nationallicence 
690 7 |a neocortex  |2 nationallicence 
690 7 |a pool of the synaptic vesicles  |2 nationallicence 
690 7 |a ultrastructure  |2 nationallicence 
700 1 |a Zhuravleva  |D Z.  |u Institute of Theoretical and Experimental Biophysics, Russian Academy of Sciences, Pushchino, Moscow Region, Russia  |4 aut 
700 1 |a Zhuravlev  |D G.  |u Institute of Cell Biophysics, Russian Academy of Science, Pushchino, Moscow Region, Russia  |4 aut 
700 1 |a Mugantseva  |D E.  |u Institute of Theoretical and Experimental Biophysics, Russian Academy of Sciences, Pushchino, Moscow Region, Russia  |4 aut 
773 0 |t Bulletin of Experimental Biology and Medicine  |d Springer US; http://www.springer-ny.com  |g 160/1(2015-11-01), 91-95  |x 0007-4888  |q 160:1<91  |1 2015  |2 160  |o 10517 
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900 7 |a Metadata rights reserved  |b Springer special CC-BY-NC licence  |2 nationallicence 
908 |D 1  |a research-article  |2 jats 
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950 |B NATIONALLICENCE  |P 856  |E 40  |u https://doi.org/10.1007/s10517-015-3106-3  |q text/html  |z Onlinezugriff via DOI 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Zhuravleva  |D Z.  |u Institute of Theoretical and Experimental Biophysics, Russian Academy of Sciences, Pushchino, Moscow Region, Russia  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Zhuravlev  |D G.  |u Institute of Cell Biophysics, Russian Academy of Science, Pushchino, Moscow Region, Russia  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Mugantseva  |D E.  |u Institute of Theoretical and Experimental Biophysics, Russian Academy of Sciences, Pushchino, Moscow Region, Russia  |4 aut 
950 |B NATIONALLICENCE  |P 773  |E 0-  |t Bulletin of Experimental Biology and Medicine  |d Springer US; http://www.springer-ny.com  |g 160/1(2015-11-01), 91-95  |x 0007-4888  |q 160:1<91  |1 2015  |2 160  |o 10517