Therapy of Chronic Cardiosclerosis in WAG Rats Using Cultures of Cardiovascular Cells Enriched with Cardiac Stem Cell

Verfasser / Beitragende:
[E. Chepeleva, S. Pavlova, A. Malakhova, E. Milevskaya, Ya. Rusakova, N. Podkhvatilina, D. Sergeevichev, E. Pokushalov, A. Karaskov, G. Sukhikh, S. Zakiyan]
Ort, Verlag, Jahr:
2015
Enthalten in:
Bulletin of Experimental Biology and Medicine, 160/1(2015-11-01), 165-173
Format:
Artikel (online)
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024 7 0 |a 10.1007/s10517-015-3119-y  |2 doi 
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245 0 0 |a Therapy of Chronic Cardiosclerosis in WAG Rats Using Cultures of Cardiovascular Cells Enriched with Cardiac Stem Cell  |h [Elektronische Daten]  |c [E. Chepeleva, S. Pavlova, A. Malakhova, E. Milevskaya, Ya. Rusakova, N. Podkhvatilina, D. Sergeevichev, E. Pokushalov, A. Karaskov, G. Sukhikh, S. Zakiyan] 
520 3 |a We developed a protocol for preparing cardiac cell culture from rat heart enriched with regional stem cells based on clonogenic properties and proliferation in culture in a medium with low serum content. Experiments on WAG rats with experimental ischemic myocardial damage showed that implantation of autologous regional stem cells into the left ventricle reduced the volume of cicatricial tissue, promoted angiogenesis in the damaged zone, and prevented the risk of heart failure development. 
540 |a Springer Science+Business Media New York, 2015 
690 7 |a cardiac stem cells  |2 nationallicence 
690 7 |a cell therapy  |2 nationallicence 
690 7 |a myocardial infarction  |2 nationallicence 
700 1 |a Chepeleva  |D E.  |u Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences, Moscow, Russia  |4 aut 
700 1 |a Pavlova  |D S.  |u Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences, Moscow, Russia  |4 aut 
700 1 |a Malakhova  |D A.  |u Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences, Moscow, Russia  |4 aut 
700 1 |a Milevskaya  |D E.  |u E. N. Meshalkin Research Institute of Circulatory Pathology, Ministry of Health of the Russian Federation, Moscow, Russia  |4 aut 
700 1 |a Rusakova  |D Ya  |u E. N. Meshalkin Research Institute of Circulatory Pathology, Ministry of Health of the Russian Federation, Moscow, Russia  |4 aut 
700 1 |a Podkhvatilina  |D N.  |u E. N. Meshalkin Research Institute of Circulatory Pathology, Ministry of Health of the Russian Federation, Moscow, Russia  |4 aut 
700 1 |a Sergeevichev  |D D.  |u E. N. Meshalkin Research Institute of Circulatory Pathology, Ministry of Health of the Russian Federation, Moscow, Russia  |4 aut 
700 1 |a Pokushalov  |D E.  |u E. N. Meshalkin Research Institute of Circulatory Pathology, Ministry of Health of the Russian Federation, Moscow, Russia  |4 aut 
700 1 |a Karaskov  |D A.  |u E. N. Meshalkin Research Institute of Circulatory Pathology, Ministry of Health of the Russian Federation, Moscow, Russia  |4 aut 
700 1 |a Sukhikh  |D G.  |u V. I. Kulakov Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of the Russian Federation, Moscow, Russia  |4 aut 
700 1 |a Zakiyan  |D S.  |u Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences, Moscow, Russia  |4 aut 
773 0 |t Bulletin of Experimental Biology and Medicine  |d Springer US; http://www.springer-ny.com  |g 160/1(2015-11-01), 165-173  |x 0007-4888  |q 160:1<165  |1 2015  |2 160  |o 10517 
856 4 0 |u https://doi.org/10.1007/s10517-015-3119-y  |q text/html  |z Onlinezugriff via DOI 
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950 |B NATIONALLICENCE  |P 700  |E 1-  |a Chepeleva  |D E.  |u Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences, Moscow, Russia  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Pavlova  |D S.  |u Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences, Moscow, Russia  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Malakhova  |D A.  |u Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences, Moscow, Russia  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Milevskaya  |D E.  |u E. N. Meshalkin Research Institute of Circulatory Pathology, Ministry of Health of the Russian Federation, Moscow, Russia  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Rusakova  |D Ya  |u E. N. Meshalkin Research Institute of Circulatory Pathology, Ministry of Health of the Russian Federation, Moscow, Russia  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Podkhvatilina  |D N.  |u E. N. Meshalkin Research Institute of Circulatory Pathology, Ministry of Health of the Russian Federation, Moscow, Russia  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Sergeevichev  |D D.  |u E. N. Meshalkin Research Institute of Circulatory Pathology, Ministry of Health of the Russian Federation, Moscow, Russia  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Pokushalov  |D E.  |u E. N. Meshalkin Research Institute of Circulatory Pathology, Ministry of Health of the Russian Federation, Moscow, Russia  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Karaskov  |D A.  |u E. N. Meshalkin Research Institute of Circulatory Pathology, Ministry of Health of the Russian Federation, Moscow, Russia  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Sukhikh  |D G.  |u V. I. Kulakov Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of the Russian Federation, Moscow, Russia  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Zakiyan  |D S.  |u Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences, Moscow, Russia  |4 aut 
950 |B NATIONALLICENCE  |P 773  |E 0-  |t Bulletin of Experimental Biology and Medicine  |d Springer US; http://www.springer-ny.com  |g 160/1(2015-11-01), 165-173  |x 0007-4888  |q 160:1<165  |1 2015  |2 160  |o 10517