Peculiar Effects of Selective Blockade of α2-Adrenoceptor Subtypes on Cardiac Chronotropy in Newborn Rats

Verfasser / Beitragende:
[T. Zefirov, L. Khisamieva, N. Ziyatdinova, A. Zefirov]
Ort, Verlag, Jahr:
2015
Enthalten in:
Bulletin of Experimental Biology and Medicine, 160/1(2015-11-01), 6-8
Format:
Artikel (online)
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024 7 0 |a 10.1007/s10517-015-3084-5  |2 doi 
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245 0 0 |a Peculiar Effects of Selective Blockade of α2-Adrenoceptor Subtypes on Cardiac Chronotropy in Newborn Rats  |h [Elektronische Daten]  |c [T. Zefirov, L. Khisamieva, N. Ziyatdinova, A. Zefirov] 
520 3 |a We studied the effects of selective blockade of various subtypes of α2-adrenoceptors on cardiac chronotropy in newborn rats. This period in rats is characterized by the absence of adrenergic regulation of heart function. Blockade of α2A/D- and α2B-adrenoceptors in 1-weekold rats provoked tachycardia. In contrast, blockade of α2C-adrenoceptors in newborn rats had no effect on heart rate. 
540 |a Springer Science+Business Media New York, 2015 
690 7 |a heart  |2 nationallicence 
690 7 |a chronotropy  |2 nationallicence 
690 7 |a α2-adrenoceptors  |2 nationallicence 
690 7 |a ontogeny  |2 nationallicence 
690 7 |a rats  |2 nationallicence 
700 1 |a Zefirov  |D T.  |u Department of Anatomy, Physiology, and Human Health Protection, Kazan (Volga Region) Federal University, Kazan, Russia  |4 aut 
700 1 |a Khisamieva  |D L.  |u Department of Anatomy, Physiology, and Human Health Protection, Kazan (Volga Region) Federal University, Kazan, Russia  |4 aut 
700 1 |a Ziyatdinova  |D N.  |u Department of Anatomy, Physiology, and Human Health Protection, Kazan (Volga Region) Federal University, Kazan, Russia  |4 aut 
700 1 |a Zefirov  |D A.  |u Department of Normal Physiology, Kazan Federal Medical University, Kazan, Russia  |4 aut 
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950 |B NATIONALLICENCE  |P 700  |E 1-  |a Zefirov  |D T.  |u Department of Anatomy, Physiology, and Human Health Protection, Kazan (Volga Region) Federal University, Kazan, Russia  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Khisamieva  |D L.  |u Department of Anatomy, Physiology, and Human Health Protection, Kazan (Volga Region) Federal University, Kazan, Russia  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Ziyatdinova  |D N.  |u Department of Anatomy, Physiology, and Human Health Protection, Kazan (Volga Region) Federal University, Kazan, Russia  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Zefirov  |D A.  |u Department of Normal Physiology, Kazan Federal Medical University, Kazan, Russia  |4 aut 
950 |B NATIONALLICENCE  |P 773  |E 0-  |t Bulletin of Experimental Biology and Medicine  |d Springer US; http://www.springer-ny.com  |g 160/1(2015-11-01), 6-8  |x 0007-4888  |q 160:1<6  |1 2015  |2 160  |o 10517