Study of Subchronic Toxicity of Relatox on Sexually Immature Animals
Gespeichert in:
Verfasser / Beitragende:
[A. Churin, T. Fomina, L. Ermolaeva, T. Vetoshkina, T. Dubskaya, T. Lamzina, E. Fedorova, O. Neupokoeva, A. Nikiforova]
Ort, Verlag, Jahr:
2015
Enthalten in:
Bulletin of Experimental Biology and Medicine, 160/1(2015-11-01), 53-56
Format:
Artikel (online)
Online Zugang:
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| 245 | 0 | 0 | |a Study of Subchronic Toxicity of Relatox on Sexually Immature Animals |h [Elektronische Daten] |c [A. Churin, T. Fomina, L. Ermolaeva, T. Vetoshkina, T. Dubskaya, T. Lamzina, E. Fedorova, O. Neupokoeva, A. Nikiforova] |
| 520 | 3 | |a Intramuscular injections of Relatox in therapeutic and toxic doses to young outbred laboratory rats for 14 days caused no changes in the peripheral blood and bone marrow parameters, serum biochemical parameters, and morphology of the major viscera. In the toxic dose, the drug caused local irritation (inflammation, atrophy, and sclerosis in muscle tissue). Regeneration processes started in muscle tissue 7 days after Relatox withdrawal. | |
| 540 | |a Springer Science+Business Media New York, 2015 | ||
| 690 | 7 | |a Relatox |2 nationallicence | |
| 690 | 7 | |a subchronic toxicity |2 nationallicence | |
| 690 | 7 | |a young rats |2 nationallicence | |
| 690 | 7 | |a botulinum toxin A |2 nationallicence | |
| 690 | 7 | |a preclinical studies |2 nationallicence | |
| 700 | 1 | |a Churin |D A. |u E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk, Russia |4 aut | |
| 700 | 1 | |a Fomina |D T. |u E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk, Russia |4 aut | |
| 700 | 1 | |a Ermolaeva |D L. |u E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk, Russia |4 aut | |
| 700 | 1 | |a Vetoshkina |D T. |u E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk, Russia |4 aut | |
| 700 | 1 | |a Dubskaya |D T. |u E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk, Russia |4 aut | |
| 700 | 1 | |a Lamzina |D T. |u E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk, Russia |4 aut | |
| 700 | 1 | |a Fedorova |D E. |u E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk, Russia |4 aut | |
| 700 | 1 | |a Neupokoeva |D O. |u E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk, Russia |4 aut | |
| 700 | 1 | |a Nikiforova |D A. |u Microgen Research-and-Production Center for Medical and Immunobiological Drugs, Ministry of Health of the Russian Federation, Moscow, Russia |4 aut | |
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| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Churin |D A. |u E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Fomina |D T. |u E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Ermolaeva |D L. |u E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Vetoshkina |D T. |u E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Dubskaya |D T. |u E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Lamzina |D T. |u E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Fedorova |D E. |u E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Neupokoeva |D O. |u E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Nikiforova |D A. |u Microgen Research-and-Production Center for Medical and Immunobiological Drugs, Ministry of Health of the Russian Federation, Moscow, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 773 |E 0- |t Bulletin of Experimental Biology and Medicine |d Springer US; http://www.springer-ny.com |g 160/1(2015-11-01), 53-56 |x 0007-4888 |q 160:1<53 |1 2015 |2 160 |o 10517 | ||