Identifi cation of Central Nervous System Proteins in Human Blood Serum and Plasma
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| 024 | 7 | 0 | |a 10.1007/s10517-015-3092-5 |2 doi |
| 035 | |a (NATIONALLICENCE)springer-10.1007/s10517-015-3092-5 | ||
| 245 | 0 | 0 | |a Identifi cation of Central Nervous System Proteins in Human Blood Serum and Plasma |h [Elektronische Daten] |c [Yu. Miroshnichenko, N. Petushkova, N. Teryaeva, A. Lisitsa, V. Zgoda, A. Belyaev, A. Potapov] |
| 520 | 3 | |a Mass-spectrometric identification of proteins in human blood plasma and serum was performed by comparing mass-spectra of fragmented peptides using Swiss-Prot and UniProtKB databases of amino acid sequences. After choosing the appropriate identification conditions we found that combination of spectrum search parameters are optimal for identification of CNS proteins. In the studied plasma and serum samples, 9 proteins involved into pathological processes in the nervous tissue were identified; 7 of them were identified in both plasma and serum. | |
| 540 | |a Springer Science+Business Media New York, 2015 | ||
| 690 | 7 | |a protein identification |2 nationallicence | |
| 690 | 7 | |a neurodegenerative diseases |2 nationallicence | |
| 690 | 7 | |a pathology of the central nervous system |2 nationallicence | |
| 690 | 7 | |a brain damage |2 nationallicence | |
| 690 | 7 | |a proteomics |2 nationallicence | |
| 700 | 1 | |a Miroshnichenko |D Yu |u V. N. Orekhovich Research Institute of Biomedical Chemistry, Moscow, Russia |4 aut | |
| 700 | 1 | |a Petushkova |D N. |u V. N. Orekhovich Research Institute of Biomedical Chemistry, Moscow, Russia |4 aut | |
| 700 | 1 | |a Teryaeva |D N. |u N. N. Burdenko Research Institute of Neurosurgery, Russian Academy of Medical Sciences, Moscow, Russia |4 aut | |
| 700 | 1 | |a Lisitsa |D A. |u V. N. Orekhovich Research Institute of Biomedical Chemistry, Moscow, Russia |4 aut | |
| 700 | 1 | |a Zgoda |D V. |u V. N. Orekhovich Research Institute of Biomedical Chemistry, Moscow, Russia |4 aut | |
| 700 | 1 | |a Belyaev |D A. |u V. N. Orekhovich Research Institute of Biomedical Chemistry, Moscow, Russia |4 aut | |
| 700 | 1 | |a Potapov |D A. |u N. N. Burdenko Research Institute of Neurosurgery, Russian Academy of Medical Sciences, Moscow, Russia |4 aut | |
| 773 | 0 | |t Bulletin of Experimental Biology and Medicine |d Springer US; http://www.springer-ny.com |g 160/1(2015-11-01), 35-39 |x 0007-4888 |q 160:1<35 |1 2015 |2 160 |o 10517 | |
| 856 | 4 | 0 | |u https://doi.org/10.1007/s10517-015-3092-5 |q text/html |z Onlinezugriff via DOI |
| 898 | |a BK010053 |b XK010053 |c XK010000 | ||
| 900 | 7 | |a Metadata rights reserved |b Springer special CC-BY-NC licence |2 nationallicence | |
| 908 | |D 1 |a research-article |2 jats | ||
| 949 | |B NATIONALLICENCE |F NATIONALLICENCE |b NL-springer | ||
| 950 | |B NATIONALLICENCE |P 856 |E 40 |u https://doi.org/10.1007/s10517-015-3092-5 |q text/html |z Onlinezugriff via DOI | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Miroshnichenko |D Yu |u V. N. Orekhovich Research Institute of Biomedical Chemistry, Moscow, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Petushkova |D N. |u V. N. Orekhovich Research Institute of Biomedical Chemistry, Moscow, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Teryaeva |D N. |u N. N. Burdenko Research Institute of Neurosurgery, Russian Academy of Medical Sciences, Moscow, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Lisitsa |D A. |u V. N. Orekhovich Research Institute of Biomedical Chemistry, Moscow, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Zgoda |D V. |u V. N. Orekhovich Research Institute of Biomedical Chemistry, Moscow, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Belyaev |D A. |u V. N. Orekhovich Research Institute of Biomedical Chemistry, Moscow, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Potapov |D A. |u N. N. Burdenko Research Institute of Neurosurgery, Russian Academy of Medical Sciences, Moscow, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 773 |E 0- |t Bulletin of Experimental Biology and Medicine |d Springer US; http://www.springer-ny.com |g 160/1(2015-11-01), 35-39 |x 0007-4888 |q 160:1<35 |1 2015 |2 160 |o 10517 | ||