caa a22 4500 605537054 CHVBK 20210128100855.0 cr unu---uuuuu 210128e20151101xx s 000 0 eng 10.1007/s10517-015-3092-5 doi (NATIONALLICENCE)springer-10.1007/s10517-015-3092-5 Identifi cation of Central Nervous System Proteins in Human Blood Serum and Plasma [Elektronische Daten] [Yu. Miroshnichenko, N. Petushkova, N. Teryaeva, A. Lisitsa, V. Zgoda, A. Belyaev, A. Potapov] Mass-spectrometric identification of proteins in human blood plasma and serum was performed by comparing mass-spectra of fragmented peptides using Swiss-Prot and UniProtKB databases of amino acid sequences. After choosing the appropriate identification conditions we found that combination of spectrum search parameters are optimal for identification of CNS proteins. In the studied plasma and serum samples, 9 proteins involved into pathological processes in the nervous tissue were identified; 7 of them were identified in both plasma and serum. Springer Science+Business Media New York, 2015 protein identification nationallicence neurodegenerative diseases nationallicence pathology of the central nervous system nationallicence brain damage nationallicence proteomics nationallicence Miroshnichenko Yu V. N. Orekhovich Research Institute of Biomedical Chemistry, Moscow, Russia aut Petushkova N. V. N. Orekhovich Research Institute of Biomedical Chemistry, Moscow, Russia aut Teryaeva N. N. N. Burdenko Research Institute of Neurosurgery, Russian Academy of Medical Sciences, Moscow, Russia aut Lisitsa A. V. N. Orekhovich Research Institute of Biomedical Chemistry, Moscow, Russia aut Zgoda V. V. N. Orekhovich Research Institute of Biomedical Chemistry, Moscow, Russia aut Belyaev A. V. N. Orekhovich Research Institute of Biomedical Chemistry, Moscow, Russia aut Potapov A. N. N. Burdenko Research Institute of Neurosurgery, Russian Academy of Medical Sciences, Moscow, Russia aut Bulletin of Experimental Biology and Medicine Springer US; http://www.springer-ny.com 160/1(2015-11-01), 35-39 0007-4888 160:1<35 2015 160 10517 https://doi.org/10.1007/s10517-015-3092-5 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s10517-015-3092-5 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Miroshnichenko Yu V. N. Orekhovich Research Institute of Biomedical Chemistry, Moscow, Russia aut NATIONALLICENCE 700 1- Petushkova N. V. N. Orekhovich Research Institute of Biomedical Chemistry, Moscow, Russia aut NATIONALLICENCE 700 1- Teryaeva N. N. N. Burdenko Research Institute of Neurosurgery, Russian Academy of Medical Sciences, Moscow, Russia aut NATIONALLICENCE 700 1- Lisitsa A. V. N. Orekhovich Research Institute of Biomedical Chemistry, Moscow, Russia aut NATIONALLICENCE 700 1- Zgoda V. V. N. Orekhovich Research Institute of Biomedical Chemistry, Moscow, Russia aut NATIONALLICENCE 700 1- Belyaev A. V. N. Orekhovich Research Institute of Biomedical Chemistry, Moscow, Russia aut NATIONALLICENCE 700 1- Potapov A. N. N. Burdenko Research Institute of Neurosurgery, Russian Academy of Medical Sciences, Moscow, Russia aut NATIONALLICENCE 773 0- Bulletin of Experimental Biology and Medicine Springer US; http://www.springer-ny.com 160/1(2015-11-01), 35-39 0007-4888 160:1<35 2015 160 10517