State of Stress-Marker Organs in Rats with Various Behavioral Characteristics during Repeated Stress Exposures

Verfasser / Beitragende:
[S. Pertsov, O. Grigorchuk, E. Koplik, A. Abramova, N. Chekmareva, V. Chekhlov]
Ort, Verlag, Jahr:
2015
Enthalten in:
Bulletin of Experimental Biology and Medicine, 160/1(2015-11-01), 20-23
Format:
Artikel (online)
ID: 605537062
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024 7 0 |a 10.1007/s10517-015-3088-1  |2 doi 
035 |a (NATIONALLICENCE)springer-10.1007/s10517-015-3088-1 
245 0 0 |a State of Stress-Marker Organs in Rats with Various Behavioral Characteristics during Repeated Stress Exposures  |h [Elektronische Daten]  |c [S. Pertsov, O. Grigorchuk, E. Koplik, A. Abramova, N. Chekmareva, V. Chekhlov] 
520 3 |a Changes in the relative weight of stress-marker organs in rats with various behavioral patterns in the open-field test were studied after repeated stress exposures on the model of daily 4-h immobilization over 8 days. Involution of the thymus and spleen in behaviorally passive specimens was found after single stress, as well as under conditions of 3- and 8-fold immobilizations. The weight of these organs in active animals remained practically unchanged after acute stress, but decreased on day 3 and particularly on day 8 of repeated stress exposures. As differentiated from passive rats (open-field test), behaviorally active specimens were characterized by hypertrophy of the adrenal glands after single and 3-fold stress procedures. Our results complement the data on individual features of the peripheral and central mechanisms for the stress response in mammals. These data illustrate the importance of individual approach to studying systemic organization of physiological functions under normal conditions and during negative emotiogenic exposures. 
540 |a Springer Science+Business Media New York, 2015 
690 7 |a repeated stress exposures  |2 nationallicence 
690 7 |a stress-marker organs  |2 nationallicence 
690 7 |a behaviorally passive and active rats  |2 nationallicence 
700 1 |a Pertsov  |D S.  |u P. K. Anokhin Research Institute of Normal Physiology, Moscow, Russia  |4 aut 
700 1 |a Grigorchuk  |D O.  |u P. K. Anokhin Research Institute of Normal Physiology, Moscow, Russia  |4 aut 
700 1 |a Koplik  |D E.  |u P. K. Anokhin Research Institute of Normal Physiology, Moscow, Russia  |4 aut 
700 1 |a Abramova  |D A.  |u P. K. Anokhin Research Institute of Normal Physiology, Moscow, Russia  |4 aut 
700 1 |a Chekmareva  |D N.  |u P. K. Anokhin Research Institute of Normal Physiology, Moscow, Russia  |4 aut 
700 1 |a Chekhlov  |D V.  |u A. I. Evdokimov Moscow State Medical and Dental University, Ministry of Health of the Russian Federation, Moscow, Russia  |4 aut 
773 0 |t Bulletin of Experimental Biology and Medicine  |d Springer US; http://www.springer-ny.com  |g 160/1(2015-11-01), 20-23  |x 0007-4888  |q 160:1<20  |1 2015  |2 160  |o 10517 
856 4 0 |u https://doi.org/10.1007/s10517-015-3088-1  |q text/html  |z Onlinezugriff via DOI 
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900 7 |a Metadata rights reserved  |b Springer special CC-BY-NC licence  |2 nationallicence 
908 |D 1  |a research-article  |2 jats 
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950 |B NATIONALLICENCE  |P 700  |E 1-  |a Pertsov  |D S.  |u P. K. Anokhin Research Institute of Normal Physiology, Moscow, Russia  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Grigorchuk  |D O.  |u P. K. Anokhin Research Institute of Normal Physiology, Moscow, Russia  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Koplik  |D E.  |u P. K. Anokhin Research Institute of Normal Physiology, Moscow, Russia  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Abramova  |D A.  |u P. K. Anokhin Research Institute of Normal Physiology, Moscow, Russia  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Chekmareva  |D N.  |u P. K. Anokhin Research Institute of Normal Physiology, Moscow, Russia  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Chekhlov  |D V.  |u A. I. Evdokimov Moscow State Medical and Dental University, Ministry of Health of the Russian Federation, Moscow, Russia  |4 aut 
950 |B NATIONALLICENCE  |P 773  |E 0-  |t Bulletin of Experimental Biology and Medicine  |d Springer US; http://www.springer-ny.com  |g 160/1(2015-11-01), 20-23  |x 0007-4888  |q 160:1<20  |1 2015  |2 160  |o 10517