Age-Specific Peculiarities of Modulation of Blood Aldo-Keto Reductase Isoenzyme Spectrum

Verfasser / Beitragende:
[V. Davydov]
Ort, Verlag, Jahr:
2015
Enthalten in:
Bulletin of Experimental Biology and Medicine, 160/2(2015-12-01), 199-201
Format:
Artikel (online)
ID: 605537089
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024 7 0 |a 10.1007/s10517-015-3127-y  |2 doi 
035 |a (NATIONALLICENCE)springer-10.1007/s10517-015-3127-y 
100 1 |a Davydov  |D V.  |u I. P. Pavlov Ryazan' State Medical University, Ministry of Health of the Russian Federation, Ryazan', Russia  |4 aut 
245 1 0 |a Age-Specific Peculiarities of Modulation of Blood Aldo-Keto Reductase Isoenzyme Spectrum  |h [Elektronische Daten]  |c [V. Davydov] 
520 3 |a The aldo-keto reductase spectrum of the blood was studied at different stages of ontogeny to elucidate the role of reduction pathway in utilization of the carbonyl products of free radical oxidation in modulation of organism sensitivity to the damaging effect of stress during ontogeny. The studies revealed the age-specific changes in aldo-keto reductase spectrum in the blood. An analogy of the aldo-keto reductase spectrum structure in animals of early maturity and in old rats was found. The appearance of age specificity of the aldo-keto reductase spectrum in the blood creates metabolic prerequisites for changes in the efficiency of utilization of carbonyl products of free radical oxidation via their reductive transformation. 
540 |a Springer Science+Business Media New York, 2015 
690 7 |a aldo-keto reductases  |2 nationallicence 
690 7 |a carbonyl stress  |2 nationallicence 
690 7 |a ontogeny  |2 nationallicence 
773 0 |t Bulletin of Experimental Biology and Medicine  |d Springer US; http://www.springer-ny.com  |g 160/2(2015-12-01), 199-201  |x 0007-4888  |q 160:2<199  |1 2015  |2 160  |o 10517 
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900 7 |a Metadata rights reserved  |b Springer special CC-BY-NC licence  |2 nationallicence 
908 |D 1  |a research-article  |2 jats 
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950 |B NATIONALLICENCE  |P 100  |E 1-  |a Davydov  |D V.  |u I. P. Pavlov Ryazan' State Medical University, Ministry of Health of the Russian Federation, Ryazan', Russia  |4 aut 
950 |B NATIONALLICENCE  |P 773  |E 0-  |t Bulletin of Experimental Biology and Medicine  |d Springer US; http://www.springer-ny.com  |g 160/2(2015-12-01), 199-201  |x 0007-4888  |q 160:2<199  |1 2015  |2 160  |o 10517