caa a22 4500 605537089 CHVBK 20210128100855.0 cr unu---uuuuu 210128e20151201xx s 000 0 eng 10.1007/s10517-015-3127-y doi (NATIONALLICENCE)springer-10.1007/s10517-015-3127-y Davydov V. I. P. Pavlov Ryazan' State Medical University, Ministry of Health of the Russian Federation, Ryazan', Russia aut Age-Specific Peculiarities of Modulation of Blood Aldo-Keto Reductase Isoenzyme Spectrum [Elektronische Daten] [V. Davydov] The aldo-keto reductase spectrum of the blood was studied at different stages of ontogeny to elucidate the role of reduction pathway in utilization of the carbonyl products of free radical oxidation in modulation of organism sensitivity to the damaging effect of stress during ontogeny. The studies revealed the age-specific changes in aldo-keto reductase spectrum in the blood. An analogy of the aldo-keto reductase spectrum structure in animals of early maturity and in old rats was found. The appearance of age specificity of the aldo-keto reductase spectrum in the blood creates metabolic prerequisites for changes in the efficiency of utilization of carbonyl products of free radical oxidation via their reductive transformation. Springer Science+Business Media New York, 2015 aldo-keto reductases nationallicence carbonyl stress nationallicence ontogeny nationallicence Bulletin of Experimental Biology and Medicine Springer US; http://www.springer-ny.com 160/2(2015-12-01), 199-201 0007-4888 160:2<199 2015 160 10517 https://doi.org/10.1007/s10517-015-3127-y text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s10517-015-3127-y text/html Onlinezugriff via DOI NATIONALLICENCE 100 1- Davydov V. I. P. Pavlov Ryazan' State Medical University, Ministry of Health of the Russian Federation, Ryazan', Russia aut NATIONALLICENCE 773 0- Bulletin of Experimental Biology and Medicine Springer US; http://www.springer-ny.com 160/2(2015-12-01), 199-201 0007-4888 160:2<199 2015 160 10517