Activity of Heme Synthesis Enzymes in the Bone Marrow and Liver of August and Wistar Rats During the Neonatal Period and After Acute Postnatal Hypoxia

Verfasser / Beitragende:
[S. Kolesnikov, A. Popova, L. Krupitskaya, A. Sinitskii, L. Kolesnikova]
Ort, Verlag, Jahr:
2015
Enthalten in:
Bulletin of Experimental Biology and Medicine, 160/2(2015-12-01), 193-195
Format:
Artikel (online)
ID: 605537127
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024 7 0 |a 10.1007/s10517-015-3125-0  |2 doi 
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245 0 0 |a Activity of Heme Synthesis Enzymes in the Bone Marrow and Liver of August and Wistar Rats During the Neonatal Period and After Acute Postnatal Hypoxia  |h [Elektronische Daten]  |c [S. Kolesnikov, A. Popova, L. Krupitskaya, A. Sinitskii, L. Kolesnikova] 
520 3 |a Activity of heme synthesis enzymes in newborn August and Wistar rats was studied after acute hypoxic hypoxia. Daily production of erythrocytes and activities of aminolevulinate synthase, aminolevulinate dehydratase, and heme synthetase were measured in the bone marrow (15-30 min after birth and on days 1 and 3 of life) and liver (day 3 after birth). Hypoxia was followed by a decrease in activity of heme synthesis enzymes in the liver (especially in August rats) and reduction of the daily erythrocyte production (especially in Wistar rats). Our results suggest that the response of heme synthesis enzymes to hypoxic exposure in newborn rats is genetically determined. The observed changes are more pronounced in Wistar rats. 
540 |a Springer Science+Business Media New York, 2015 
690 7 |a heme synthesis enzymes  |2 nationallicence 
690 7 |a acute hypoxia  |2 nationallicence 
690 7 |a neonatal period  |2 nationallicence 
690 7 |a August and Wistar rats  |2 nationallicence 
700 1 |a Kolesnikov  |D S.  |u Research Center for Problems of Family Health and Human Reproduction, Irkutsk, Russia  |4 aut 
700 1 |a Popova  |D A.  |u Municipal Clinical Hospital No. 6, Moscow, Russia  |4 aut 
700 1 |a Krupitskaya  |D L.  |u South Ural State Medical University, Ministry of Health of the Russian Federation, Chelyabinsk, Russia  |4 aut 
700 1 |a Sinitskii  |D A.  |u South Ural State Medical University, Ministry of Health of the Russian Federation, Chelyabinsk, Russia  |4 aut 
700 1 |a Kolesnikova  |D L.  |u Research Center for Problems of Family Health and Human Reproduction, Irkutsk, Russia  |4 aut 
773 0 |t Bulletin of Experimental Biology and Medicine  |d Springer US; http://www.springer-ny.com  |g 160/2(2015-12-01), 193-195  |x 0007-4888  |q 160:2<193  |1 2015  |2 160  |o 10517 
856 4 0 |u https://doi.org/10.1007/s10517-015-3125-0  |q text/html  |z Onlinezugriff via DOI 
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900 7 |a Metadata rights reserved  |b Springer special CC-BY-NC licence  |2 nationallicence 
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950 |B NATIONALLICENCE  |P 856  |E 40  |u https://doi.org/10.1007/s10517-015-3125-0  |q text/html  |z Onlinezugriff via DOI 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Kolesnikov  |D S.  |u Research Center for Problems of Family Health and Human Reproduction, Irkutsk, Russia  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Popova  |D A.  |u Municipal Clinical Hospital No. 6, Moscow, Russia  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Krupitskaya  |D L.  |u South Ural State Medical University, Ministry of Health of the Russian Federation, Chelyabinsk, Russia  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Sinitskii  |D A.  |u South Ural State Medical University, Ministry of Health of the Russian Federation, Chelyabinsk, Russia  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Kolesnikova  |D L.  |u Research Center for Problems of Family Health and Human Reproduction, Irkutsk, Russia  |4 aut 
950 |B NATIONALLICENCE  |P 773  |E 0-  |t Bulletin of Experimental Biology and Medicine  |d Springer US; http://www.springer-ny.com  |g 160/2(2015-12-01), 193-195  |x 0007-4888  |q 160:2<193  |1 2015  |2 160  |o 10517