caa a22 4500 605537151 CHVBK 20210128100856.0 cr unu---uuuuu 210128e20151201xx s 000 0 eng 10.1007/s10517-015-3151-y doi (NATIONALLICENCE)springer-10.1007/s10517-015-3151-y Serum Glutathione in Patients with Schizophrenia in Dynamics of Antipsychotic Therapy [Elektronische Daten] [S. Ivanova, L. Smirnova, Yu. Shchigoreva, A. Semke, N. Bokhan] Serum concentrations of oxidized and reduced glutathione were measured in 73 patients with schizophrenia at admission and in dynamics of therapy with traditional and atypical antipsychotic drugs. The level of reduced glutathione in patients with schizophrenia with manifest clinical symptoms was lower than in normal subjects. Atypical neuroleptics produced virtually no effects on the glutathione system, while therapy with typical antipsychotics led to further decrease in the levels of reduced glutathione, thus aggravating the imbalance of metabolic processes typical of schizophrenia. Springer Science+Business Media New York, 2015 schizophrenia nationallicence reduced glutathione nationallicence antipsychotic drugs nationallicence Ivanova S. Research Institute of Mental Health, Tomsk, Russia aut Smirnova L. Research Institute of Mental Health, Tomsk, Russia aut Shchigoreva Yu Research Institute of Mental Health, Tomsk, Russia aut Semke A. Research Institute of Mental Health, Tomsk, Russia aut Bokhan N. Research Institute of Mental Health, Tomsk, Russia aut Bulletin of Experimental Biology and Medicine Springer US; http://www.springer-ny.com 160/2(2015-12-01), 283-285 0007-4888 160:2<283 2015 160 10517 https://doi.org/10.1007/s10517-015-3151-y text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s10517-015-3151-y text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Ivanova S. Research Institute of Mental Health, Tomsk, Russia aut NATIONALLICENCE 700 1- Smirnova L. Research Institute of Mental Health, Tomsk, Russia aut NATIONALLICENCE 700 1- Shchigoreva Yu Research Institute of Mental Health, Tomsk, Russia aut NATIONALLICENCE 700 1- Semke A. Research Institute of Mental Health, Tomsk, Russia aut NATIONALLICENCE 700 1- Bokhan N. Research Institute of Mental Health, Tomsk, Russia aut NATIONALLICENCE 773 0- Bulletin of Experimental Biology and Medicine Springer US; http://www.springer-ny.com 160/2(2015-12-01), 283-285 0007-4888 160:2<283 2015 160 10517