Assessment of Nephroprotective Potential of Histochrome during Induced Arterial Hypertension

Verfasser / Beitragende:
[I. Agafonova, R. Bogdanovich, N. Kolosova]
Ort, Verlag, Jahr:
2015
Enthalten in:
Bulletin of Experimental Biology and Medicine, 160/2(2015-12-01), 223-227
Format:
Artikel (online)
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024 7 0 |a 10.1007/s10517-015-3134-z  |2 doi 
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245 0 0 |a Assessment of Nephroprotective Potential of Histochrome during Induced Arterial Hypertension  |h [Elektronische Daten]  |c [I. Agafonova, R. Bogdanovich, N. Kolosova] 
520 3 |a Magnetic resonance tomography was employed to verify endothelial dysfunction of renal arteries in Wistar and OXYS rats under conditions of induced arterial hypertension. Angiography revealed changes in the size and form of renal arteries of hypertensive animals. In hypertensive rats, histochrome exerted a benevolent therapeutic effect in renal arteries: it decreased BP, diminished thrombus formation in fi ne capillaries and arterioles, demonstrated the anticoagulant properties, partially improved endothelial dysfunction of small renal arteries, and up-regulated the glomerular filtration. 
540 |a Springer Science+Business Media New York, 2015 
690 7 |a arterial hypertension  |2 nationallicence 
690 7 |a endothelial vasomotor function  |2 nationallicence 
690 7 |a OXYS rats  |2 nationallicence 
690 7 |a magnetic resonance tomography  |2 nationallicence 
690 7 |a angiography  |2 nationallicence 
700 1 |a Agafonova  |D I.  |u G. B. Elyakov Pacific Ocean Institute of Bioorganic Chemistry, Far-East Division of Russian Academy of Sciences, Novosibirsk, Russia  |4 aut 
700 1 |a Bogdanovich  |D R.  |u Medical Association, Far-East Division of Russian Academy of Sciences, Vladivostok, Russia  |4 aut 
700 1 |a Kolosova  |D N.  |u Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences, Novosibirsk, Russia  |4 aut 
773 0 |t Bulletin of Experimental Biology and Medicine  |d Springer US; http://www.springer-ny.com  |g 160/2(2015-12-01), 223-227  |x 0007-4888  |q 160:2<223  |1 2015  |2 160  |o 10517 
856 4 0 |u https://doi.org/10.1007/s10517-015-3134-z  |q text/html  |z Onlinezugriff via DOI 
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900 7 |a Metadata rights reserved  |b Springer special CC-BY-NC licence  |2 nationallicence 
908 |D 1  |a research-article  |2 jats 
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950 |B NATIONALLICENCE  |P 856  |E 40  |u https://doi.org/10.1007/s10517-015-3134-z  |q text/html  |z Onlinezugriff via DOI 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Agafonova  |D I.  |u G. B. Elyakov Pacific Ocean Institute of Bioorganic Chemistry, Far-East Division of Russian Academy of Sciences, Novosibirsk, Russia  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Bogdanovich  |D R.  |u Medical Association, Far-East Division of Russian Academy of Sciences, Vladivostok, Russia  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Kolosova  |D N.  |u Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences, Novosibirsk, Russia  |4 aut 
950 |B NATIONALLICENCE  |P 773  |E 0-  |t Bulletin of Experimental Biology and Medicine  |d Springer US; http://www.springer-ny.com  |g 160/2(2015-12-01), 223-227  |x 0007-4888  |q 160:2<223  |1 2015  |2 160  |o 10517