Study of Cytokine Profile of Cultured "Early” and "Late” Endothelial Progenitor Cells in Peripheral Blood of Chronic Heart Failure Patients after Mobilization Course with Granulocyte Colony-Stimulating Factor

Verfasser / Beitragende:
[N. Bondarenko, O. Poveshchenko, A. Lykov, I. Kim, M. Surovtseva, A. Poveshchenko, E. Pokushalov, A. Romanov, A. Karas'kov, V. Konenkov]
Ort, Verlag, Jahr:
2015
Enthalten in:
Bulletin of Experimental Biology and Medicine, 160/2(2015-12-01), 249-251
Format:
Artikel (online)
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024 7 0 |a 10.1007/s10517-015-3141-0  |2 doi 
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245 0 0 |a Study of Cytokine Profile of Cultured "Early” and "Late” Endothelial Progenitor Cells in Peripheral Blood of Chronic Heart Failure Patients after Mobilization Course with Granulocyte Colony-Stimulating Factor  |h [Elektronische Daten]  |c [N. Bondarenko, O. Poveshchenko, A. Lykov, I. Kim, M. Surovtseva, A. Poveshchenko, E. Pokushalov, A. Romanov, A. Karas'kov, V. Konenkov] 
520 3 |a The effect of cell culturing protocol with various adhesion proteins and different culture time on the profile of cytokine and growth factors produced by endothelial progenitor cells harvested after mobilization with granulocyte colony-stimulating factor was examined in patients with chronic heart failure. The endothelial progenitor cells cultured on fibronectin or gelatin produced a broad and overall similar spectrum of cytokines and growth factors, the levels of which depended on the culture time. On culture day 16, the cells grown on fibronectin diminished the production of cytokines and growth factors (IL-10, IL-18, IL-8, erythropoietin, and VEGF), while the cells grown on gelatin down-regulated the synthesis of TNF-α, IL-8, and erythropoietin, although they up-regulated the production of IL-10, IL-18, and VEGF. 
540 |a Springer Science+Business Media New York, 2015 
690 7 |a endothelial progenitor cells  |2 nationallicence 
690 7 |a cytokines  |2 nationallicence 
690 7 |a growth factors  |2 nationallicence 
690 7 |a chronic heart failure  |2 nationallicence 
700 1 |a Bondarenko  |D N.  |u Research Institute of Experimental and Clinical Lymphology, Siberian Division of the Russian Academy of Medical Sciences, Novosibirsk, Russia  |4 aut 
700 1 |a Poveshchenko  |D O.  |u Research Institute of Experimental and Clinical Lymphology, Siberian Division of the Russian Academy of Medical Sciences, Novosibirsk, Russia  |4 aut 
700 1 |a Lykov  |D A.  |u Research Institute of Experimental and Clinical Lymphology, Siberian Division of the Russian Academy of Medical Sciences, Novosibirsk, Russia  |4 aut 
700 1 |a Kim  |D I.  |u Research Institute of Experimental and Clinical Lymphology, Siberian Division of the Russian Academy of Medical Sciences, Novosibirsk, Russia  |4 aut 
700 1 |a Surovtseva  |D M.  |u Research Institute of Experimental and Clinical Lymphology, Siberian Division of the Russian Academy of Medical Sciences, Novosibirsk, Russia  |4 aut 
700 1 |a Poveshchenko  |D A.  |u Research Institute of Experimental and Clinical Lymphology, Siberian Division of the Russian Academy of Medical Sciences, Novosibirsk, Russia  |4 aut 
700 1 |a Pokushalov  |D E.  |u E. N. Meshalkin Novosibirsk Research Institute of Circulation Pathology, Ministry of Health of the Russian Federation, Novosibirsk, Russia  |4 aut 
700 1 |a Romanov  |D A.  |u E. N. Meshalkin Novosibirsk Research Institute of Circulation Pathology, Ministry of Health of the Russian Federation, Novosibirsk, Russia  |4 aut 
700 1 |a Karas'kov  |D A.  |u E. N. Meshalkin Novosibirsk Research Institute of Circulation Pathology, Ministry of Health of the Russian Federation, Novosibirsk, Russia  |4 aut 
700 1 |a Konenkov  |D V.  |u Research Institute of Experimental and Clinical Lymphology, Siberian Division of the Russian Academy of Medical Sciences, Novosibirsk, Russia  |4 aut 
773 0 |t Bulletin of Experimental Biology and Medicine  |d Springer US; http://www.springer-ny.com  |g 160/2(2015-12-01), 249-251  |x 0007-4888  |q 160:2<249  |1 2015  |2 160  |o 10517 
856 4 0 |u https://doi.org/10.1007/s10517-015-3141-0  |q text/html  |z Onlinezugriff via DOI 
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950 |B NATIONALLICENCE  |P 700  |E 1-  |a Bondarenko  |D N.  |u Research Institute of Experimental and Clinical Lymphology, Siberian Division of the Russian Academy of Medical Sciences, Novosibirsk, Russia  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Poveshchenko  |D O.  |u Research Institute of Experimental and Clinical Lymphology, Siberian Division of the Russian Academy of Medical Sciences, Novosibirsk, Russia  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Lykov  |D A.  |u Research Institute of Experimental and Clinical Lymphology, Siberian Division of the Russian Academy of Medical Sciences, Novosibirsk, Russia  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Kim  |D I.  |u Research Institute of Experimental and Clinical Lymphology, Siberian Division of the Russian Academy of Medical Sciences, Novosibirsk, Russia  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Surovtseva  |D M.  |u Research Institute of Experimental and Clinical Lymphology, Siberian Division of the Russian Academy of Medical Sciences, Novosibirsk, Russia  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Poveshchenko  |D A.  |u Research Institute of Experimental and Clinical Lymphology, Siberian Division of the Russian Academy of Medical Sciences, Novosibirsk, Russia  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Pokushalov  |D E.  |u E. N. Meshalkin Novosibirsk Research Institute of Circulation Pathology, Ministry of Health of the Russian Federation, Novosibirsk, Russia  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Romanov  |D A.  |u E. N. Meshalkin Novosibirsk Research Institute of Circulation Pathology, Ministry of Health of the Russian Federation, Novosibirsk, Russia  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Karas'kov  |D A.  |u E. N. Meshalkin Novosibirsk Research Institute of Circulation Pathology, Ministry of Health of the Russian Federation, Novosibirsk, Russia  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Konenkov  |D V.  |u Research Institute of Experimental and Clinical Lymphology, Siberian Division of the Russian Academy of Medical Sciences, Novosibirsk, Russia  |4 aut 
950 |B NATIONALLICENCE  |P 773  |E 0-  |t Bulletin of Experimental Biology and Medicine  |d Springer US; http://www.springer-ny.com  |g 160/2(2015-12-01), 249-251  |x 0007-4888  |q 160:2<249  |1 2015  |2 160  |o 10517