Serum Concentration of Growth Factors in Dogs under Different Conditions of Distraction Osteogenesis
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| 024 | 7 | 0 | |a 10.1007/s10517-015-3131-2 |2 doi |
| 035 | |a (NATIONALLICENCE)springer-10.1007/s10517-015-3131-2 | ||
| 245 | 0 | 0 | |a Serum Concentration of Growth Factors in Dogs under Different Conditions of Distraction Osteogenesis |h [Elektronische Daten] |c [M. Stogov, N. Tushina, A. Emanov] |
| 520 | 3 | |a Concentrations of insulin-like growth factors 1 and 2 (IGF-1 and IGF-2), stem cell factor (SCF), vascular endothelial growth factor (VEGF), and transforming growth factor β1 (TGF-β1) were measured in the blood serum of dogs subjected to experimental lengthening of shin bones. In animals subjected to shin bone lengthening at a rate of 1 mm/day in 4 steps, the concentrations of SCF and TGF-β1 significantly increased in the middle of distraction and IGF-1 concentration increased by the end of distraction. In animals subjected to lengthening at a rate of 1.5 mm/day in 6 steps, the levels of IGF-1 and TGF-β1 significantly increased in the middle of distraction and the concentration of IGF-2 at the end of distraction. In animals subjected to lengthening at a rate of 3 mm/day in 120 steps, the concentrations of IGF-1 and TGF-β1 significantly decreased in the middle of distraction and concentrations of IGF-1, VEGF, and TGF-β1 increased by the end of distraction. | |
| 540 | |a Springer Science+Business Media New York, 2015 | ||
| 690 | 7 | |a growth factors |2 nationallicence | |
| 690 | 7 | |a blood serum |2 nationallicence | |
| 690 | 7 | |a distraction osteogenesis |2 nationallicence | |
| 700 | 1 | |a Stogov |D M. |u G. A. Ilizarov Russian Research Center for Restorative Traumatology and Orthopaedics, Ministry of Health of the Russian Federation, Kurgan, Russia |4 aut | |
| 700 | 1 | |a Tushina |D N. |u G. A. Ilizarov Russian Research Center for Restorative Traumatology and Orthopaedics, Ministry of Health of the Russian Federation, Kurgan, Russia |4 aut | |
| 700 | 1 | |a Emanov |D A. |u G. A. Ilizarov Russian Research Center for Restorative Traumatology and Orthopaedics, Ministry of Health of the Russian Federation, Kurgan, Russia |4 aut | |
| 773 | 0 | |t Bulletin of Experimental Biology and Medicine |d Springer US; http://www.springer-ny.com |g 160/2(2015-12-01), 213-215 |x 0007-4888 |q 160:2<213 |1 2015 |2 160 |o 10517 | |
| 856 | 4 | 0 | |u https://doi.org/10.1007/s10517-015-3131-2 |q text/html |z Onlinezugriff via DOI |
| 898 | |a BK010053 |b XK010053 |c XK010000 | ||
| 900 | 7 | |a Metadata rights reserved |b Springer special CC-BY-NC licence |2 nationallicence | |
| 908 | |D 1 |a research-article |2 jats | ||
| 949 | |B NATIONALLICENCE |F NATIONALLICENCE |b NL-springer | ||
| 950 | |B NATIONALLICENCE |P 856 |E 40 |u https://doi.org/10.1007/s10517-015-3131-2 |q text/html |z Onlinezugriff via DOI | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Stogov |D M. |u G. A. Ilizarov Russian Research Center for Restorative Traumatology and Orthopaedics, Ministry of Health of the Russian Federation, Kurgan, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Tushina |D N. |u G. A. Ilizarov Russian Research Center for Restorative Traumatology and Orthopaedics, Ministry of Health of the Russian Federation, Kurgan, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Emanov |D A. |u G. A. Ilizarov Russian Research Center for Restorative Traumatology and Orthopaedics, Ministry of Health of the Russian Federation, Kurgan, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 773 |E 0- |t Bulletin of Experimental Biology and Medicine |d Springer US; http://www.springer-ny.com |g 160/2(2015-12-01), 213-215 |x 0007-4888 |q 160:2<213 |1 2015 |2 160 |o 10517 | ||