Features of the Structure of the Circadian Rhythm of Blood Pressure and Heart Rate under Genetically Determined Hypertension in the Experiment

Verfasser / Beitragende:
[M. Blagonravov, V. Frolov, V. Goryachev, M. Azova]
Ort, Verlag, Jahr:
2015
Enthalten in:
Bulletin of Experimental Biology and Medicine, 158/6(2015-04-01), 723-725
Format:
Artikel (online)
ID: 605537429
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024 7 0 |a 10.1007/s10517-015-2846-4  |2 doi 
035 |a (NATIONALLICENCE)springer-10.1007/s10517-015-2846-4 
245 0 0 |a Features of the Structure of the Circadian Rhythm of Blood Pressure and Heart Rate under Genetically Determined Hypertension in the Experiment  |h [Elektronische Daten]  |c [M. Blagonravov, V. Frolov, V. Goryachev, M. Azova] 
520 3 |a In SHR rats of different ages (22, 26, 30, 34, and 38 weeks), continuous 24-h telemetric monitoring of BP and HR was performed. The amplitude and power of oscillations of diastolic BP significantly decreased at the later stages of arterial hypertension (38 weeks), which was considered as a poor prognostic marker. We also observed a significant decrease in the mean daytime, nighttime, and maximum HR and mesor on weeks 30 and 34, but not on week 38, which can reflect triggering of the adaptive response followed by its exhaustion. 
540 |a Springer Science+Business Media New York, 2015 
690 7 |a blood pressure  |2 nationallicence 
690 7 |a heart rate  |2 nationallicence 
690 7 |a circadian rhythm  |2 nationallicence 
690 7 |a arterial hypertension  |2 nationallicence 
690 7 |a spontaneously hypertensive rats (SHR)  |2 nationallicence 
700 1 |a Blagonravov  |D M.  |u Department of General Pathology and Pathophysiology, Medical Faculty, People's Friendship University of Russia, Moscow, Russia  |4 aut 
700 1 |a Frolov  |D V.  |u Department of General Pathology and Pathophysiology, Medical Faculty, People's Friendship University of Russia, Moscow, Russia  |4 aut 
700 1 |a Goryachev  |D V.  |u Department of General Pathology and Pathophysiology, Medical Faculty, People's Friendship University of Russia, Moscow, Russia  |4 aut 
700 1 |a Azova  |D M.  |u Department of General Pathology and Pathophysiology, Medical Faculty, People's Friendship University of Russia, Moscow, Russia  |4 aut 
773 0 |t Bulletin of Experimental Biology and Medicine  |d Springer US; http://www.springer-ny.com  |g 158/6(2015-04-01), 723-725  |x 0007-4888  |q 158:6<723  |1 2015  |2 158  |o 10517 
856 4 0 |u https://doi.org/10.1007/s10517-015-2846-4  |q text/html  |z Onlinezugriff via DOI 
898 |a BK010053  |b XK010053  |c XK010000 
900 7 |a Metadata rights reserved  |b Springer special CC-BY-NC licence  |2 nationallicence 
908 |D 1  |a research-article  |2 jats 
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950 |B NATIONALLICENCE  |P 856  |E 40  |u https://doi.org/10.1007/s10517-015-2846-4  |q text/html  |z Onlinezugriff via DOI 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Blagonravov  |D M.  |u Department of General Pathology and Pathophysiology, Medical Faculty, People's Friendship University of Russia, Moscow, Russia  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Frolov  |D V.  |u Department of General Pathology and Pathophysiology, Medical Faculty, People's Friendship University of Russia, Moscow, Russia  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Goryachev  |D V.  |u Department of General Pathology and Pathophysiology, Medical Faculty, People's Friendship University of Russia, Moscow, Russia  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Azova  |D M.  |u Department of General Pathology and Pathophysiology, Medical Faculty, People's Friendship University of Russia, Moscow, Russia  |4 aut 
950 |B NATIONALLICENCE  |P 773  |E 0-  |t Bulletin of Experimental Biology and Medicine  |d Springer US; http://www.springer-ny.com  |g 158/6(2015-04-01), 723-725  |x 0007-4888  |q 158:6<723  |1 2015  |2 158  |o 10517