Effects of Antibiotic Treatment on the Lactobacillus Composition of Vaginal Microbiota

Verfasser / Beitragende:
[A. Melkumyan, T. Priputnevich, A. Ankirskaya, V. Murav'eva, L. Lubasovskaya]
Ort, Verlag, Jahr:
2015
Enthalten in:
Bulletin of Experimental Biology and Medicine, 158/6(2015-04-01), 766-768
Format:
Artikel (online)
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024 7 0 |a 10.1007/s10517-015-2857-1  |2 doi 
035 |a (NATIONALLICENCE)springer-10.1007/s10517-015-2857-1 
245 0 0 |a Effects of Antibiotic Treatment on the Lactobacillus Composition of Vaginal Microbiota  |h [Elektronische Daten]  |c [A. Melkumyan, T. Priputnevich, A. Ankirskaya, V. Murav'eva, L. Lubasovskaya] 
520 3 |a We analyzed sensitivity of 123 vaginal lactobacillus strains to antibacterial substances. All lactobacillus strains were sensitive to ampicillin, cefazolin, cefotaxime, and vancomycin, and insensitive to metronidazole, trimethoprim/sulfamethoxazole, and levofl oxacin. Lactobacillus strains demonstrated different sensitivity to gentamycin, clindamycin, erythromycin, ciprofl oxacin, and tetracycline. The phenomenon of preferential selective infl uence of antibacterial drugs on the composition of lactobacilli of the vaginal microbiota, in which some lactobacilli survive as part of the vaginal microbiota and have a selective advantage over other types of lactobacilli, should be taken into account during treatment of vaginal infections and dysbiosis. 
540 |a Springer Science+Business Media New York, 2015 
690 7 |a vaginal microbiota  |2 nationallicence 
690 7 |a lactobacilli  |2 nationallicence 
690 7 |a L. crispatus  |2 nationallicence 
690 7 |a L. iners  |2 nationallicence 
690 7 |a antibiotic sensitivity  |2 nationallicence 
700 1 |a Melkumyan  |D A.  |u V. I. Kulakov Research Center for Obstetrics, Gynecology, and Perinatology, Ministry of Health of the Russian Federation, Moscow, Russia  |4 aut 
700 1 |a Priputnevich  |D T.  |u V. I. Kulakov Research Center for Obstetrics, Gynecology, and Perinatology, Ministry of Health of the Russian Federation, Moscow, Russia  |4 aut 
700 1 |a Ankirskaya  |D A.  |u V. I. Kulakov Research Center for Obstetrics, Gynecology, and Perinatology, Ministry of Health of the Russian Federation, Moscow, Russia  |4 aut 
700 1 |a Murav'eva  |D V.  |u V. I. Kulakov Research Center for Obstetrics, Gynecology, and Perinatology, Ministry of Health of the Russian Federation, Moscow, Russia  |4 aut 
700 1 |a Lubasovskaya  |D L.  |u V. I. Kulakov Research Center for Obstetrics, Gynecology, and Perinatology, Ministry of Health of the Russian Federation, Moscow, Russia  |4 aut 
773 0 |t Bulletin of Experimental Biology and Medicine  |d Springer US; http://www.springer-ny.com  |g 158/6(2015-04-01), 766-768  |x 0007-4888  |q 158:6<766  |1 2015  |2 158  |o 10517 
856 4 0 |u https://doi.org/10.1007/s10517-015-2857-1  |q text/html  |z Onlinezugriff via DOI 
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908 |D 1  |a research-article  |2 jats 
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950 |B NATIONALLICENCE  |P 700  |E 1-  |a Melkumyan  |D A.  |u V. I. Kulakov Research Center for Obstetrics, Gynecology, and Perinatology, Ministry of Health of the Russian Federation, Moscow, Russia  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Priputnevich  |D T.  |u V. I. Kulakov Research Center for Obstetrics, Gynecology, and Perinatology, Ministry of Health of the Russian Federation, Moscow, Russia  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Ankirskaya  |D A.  |u V. I. Kulakov Research Center for Obstetrics, Gynecology, and Perinatology, Ministry of Health of the Russian Federation, Moscow, Russia  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Murav'eva  |D V.  |u V. I. Kulakov Research Center for Obstetrics, Gynecology, and Perinatology, Ministry of Health of the Russian Federation, Moscow, Russia  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Lubasovskaya  |D L.  |u V. I. Kulakov Research Center for Obstetrics, Gynecology, and Perinatology, Ministry of Health of the Russian Federation, Moscow, Russia  |4 aut 
950 |B NATIONALLICENCE  |P 773  |E 0-  |t Bulletin of Experimental Biology and Medicine  |d Springer US; http://www.springer-ny.com  |g 158/6(2015-04-01), 766-768  |x 0007-4888  |q 158:6<766  |1 2015  |2 158  |o 10517