caa a22 4500 605537437 CHVBK 20210128100857.0 cr unu---uuuuu 210128e20150401xx s 000 0 eng 10.1007/s10517-015-2857-1 doi (NATIONALLICENCE)springer-10.1007/s10517-015-2857-1 Effects of Antibiotic Treatment on the Lactobacillus Composition of Vaginal Microbiota [Elektronische Daten] [A. Melkumyan, T. Priputnevich, A. Ankirskaya, V. Murav'eva, L. Lubasovskaya] We analyzed sensitivity of 123 vaginal lactobacillus strains to antibacterial substances. All lactobacillus strains were sensitive to ampicillin, cefazolin, cefotaxime, and vancomycin, and insensitive to metronidazole, trimethoprim/sulfamethoxazole, and levofl oxacin. Lactobacillus strains demonstrated different sensitivity to gentamycin, clindamycin, erythromycin, ciprofl oxacin, and tetracycline. The phenomenon of preferential selective infl uence of antibacterial drugs on the composition of lactobacilli of the vaginal microbiota, in which some lactobacilli survive as part of the vaginal microbiota and have a selective advantage over other types of lactobacilli, should be taken into account during treatment of vaginal infections and dysbiosis. Springer Science+Business Media New York, 2015 vaginal microbiota nationallicence lactobacilli nationallicence L. crispatus nationallicence L. iners nationallicence antibiotic sensitivity nationallicence Melkumyan A. V. I. Kulakov Research Center for Obstetrics, Gynecology, and Perinatology, Ministry of Health of the Russian Federation, Moscow, Russia aut Priputnevich T. V. I. Kulakov Research Center for Obstetrics, Gynecology, and Perinatology, Ministry of Health of the Russian Federation, Moscow, Russia aut Ankirskaya A. V. I. Kulakov Research Center for Obstetrics, Gynecology, and Perinatology, Ministry of Health of the Russian Federation, Moscow, Russia aut Murav'eva V. V. I. Kulakov Research Center for Obstetrics, Gynecology, and Perinatology, Ministry of Health of the Russian Federation, Moscow, Russia aut Lubasovskaya L. V. I. Kulakov Research Center for Obstetrics, Gynecology, and Perinatology, Ministry of Health of the Russian Federation, Moscow, Russia aut Bulletin of Experimental Biology and Medicine Springer US; http://www.springer-ny.com 158/6(2015-04-01), 766-768 0007-4888 158:6<766 2015 158 10517 https://doi.org/10.1007/s10517-015-2857-1 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s10517-015-2857-1 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Melkumyan A. V. I. Kulakov Research Center for Obstetrics, Gynecology, and Perinatology, Ministry of Health of the Russian Federation, Moscow, Russia aut NATIONALLICENCE 700 1- Priputnevich T. V. I. Kulakov Research Center for Obstetrics, Gynecology, and Perinatology, Ministry of Health of the Russian Federation, Moscow, Russia aut NATIONALLICENCE 700 1- Ankirskaya A. V. I. Kulakov Research Center for Obstetrics, Gynecology, and Perinatology, Ministry of Health of the Russian Federation, Moscow, Russia aut NATIONALLICENCE 700 1- Murav'eva V. V. I. Kulakov Research Center for Obstetrics, Gynecology, and Perinatology, Ministry of Health of the Russian Federation, Moscow, Russia aut NATIONALLICENCE 700 1- Lubasovskaya L. V. I. Kulakov Research Center for Obstetrics, Gynecology, and Perinatology, Ministry of Health of the Russian Federation, Moscow, Russia aut NATIONALLICENCE 773 0- Bulletin of Experimental Biology and Medicine Springer US; http://www.springer-ny.com 158/6(2015-04-01), 766-768 0007-4888 158:6<766 2015 158 10517