Changes in Peripheral Blood Monocytes and Liver Macrophages in Male Rats after Benzo(a)pyrene Injection
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| 024 | 7 | 0 | |a 10.1007/s10517-015-2850-8 |2 doi |
| 035 | |a (NATIONALLICENCE)springer-10.1007/s10517-015-2850-8 | ||
| 245 | 0 | 0 | |a Changes in Peripheral Blood Monocytes and Liver Macrophages in Male Rats after Benzo(a)pyrene Injection |h [Elektronische Daten] |c [S. Kolesnikov, S. Michurina, S. Arkhipov] |
| 520 | 3 | |a Intraperitoneal injections of benzo(a)pyrene to male rats in a total dose of 60 mg/kg modified the production of ROS and the phagocytic potential of blood monocytes by modulating their potential bactericidal activity. The lysosomal system (particularly the secondary lysosomes) of liver macrophages was activated, which promoted fusion of the hydrolytic potentials of macrophages and monocytes. These results indicated that the toxin modulated the cellular immune homeostasis and the level of general nonspecific resistance. | |
| 540 | |a Springer Science+Business Media New York, 2015 | ||
| 690 | 7 | |a liver |2 nationallicence | |
| 690 | 7 | |a Kupffer's cells |2 nationallicence | |
| 690 | 7 | |a monocytes |2 nationallicence | |
| 690 | 7 | |a benzo(a)pyrene |2 nationallicence | |
| 690 | 7 | |a phagocytic activity |2 nationallicence | |
| 700 | 1 | |a Kolesnikov |D S. |u Research Center of Family Health Problems and Human Reproduction, Irkutsk, Russia |4 aut | |
| 700 | 1 | |a Michurina |D S. |u Research Institute of Clinical Immunology and Experimental Lymphology, Novosibirsk, Russia |4 aut | |
| 700 | 1 | |a Arkhipov |D S. |u Research Institute of Clinical Immunology and Experimental Lymphology, Novosibirsk, Russia |4 aut | |
| 773 | 0 | |t Bulletin of Experimental Biology and Medicine |d Springer US; http://www.springer-ny.com |g 158/6(2015-04-01), 735-738 |x 0007-4888 |q 158:6<735 |1 2015 |2 158 |o 10517 | |
| 856 | 4 | 0 | |u https://doi.org/10.1007/s10517-015-2850-8 |q text/html |z Onlinezugriff via DOI |
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| 900 | 7 | |a Metadata rights reserved |b Springer special CC-BY-NC licence |2 nationallicence | |
| 908 | |D 1 |a research-article |2 jats | ||
| 949 | |B NATIONALLICENCE |F NATIONALLICENCE |b NL-springer | ||
| 950 | |B NATIONALLICENCE |P 856 |E 40 |u https://doi.org/10.1007/s10517-015-2850-8 |q text/html |z Onlinezugriff via DOI | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Kolesnikov |D S. |u Research Center of Family Health Problems and Human Reproduction, Irkutsk, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Michurina |D S. |u Research Institute of Clinical Immunology and Experimental Lymphology, Novosibirsk, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Arkhipov |D S. |u Research Institute of Clinical Immunology and Experimental Lymphology, Novosibirsk, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 773 |E 0- |t Bulletin of Experimental Biology and Medicine |d Springer US; http://www.springer-ny.com |g 158/6(2015-04-01), 735-738 |x 0007-4888 |q 158:6<735 |1 2015 |2 158 |o 10517 | ||