caa a22 4500 605537577 CHVBK 20210128100858.0 cr unu---uuuuu 210128e20150401xx s 000 0 eng 10.1007/s10517-015-2852-6 doi (NATIONALLICENCE)springer-10.1007/s10517-015-2852-6 Structural and Functional Basis of Chronic Pelvic Pain Syndrome during Combined Chronic Cystitis and Adenomyosis [Elektronische Daten] [N. Shelkovnikova, E. Lushnikova, A. Pichigina, A. Neimark] Comprehensive clinical and morphological examination of 60 female patients with chronic pelvic pain syndrome after combined chronic cystitis and adenomyosis was carried out. In all patients, the complex urodynamic examination revealed various disturbances of urination and stasis-like abnormalities of circulation in vesical and uterine walls. The pathomorphological peculiarities of the urogenital disorders during combination of adenomyosis and cystitis (of the combined proliferative and erosive/destructive type) is manifested by more pronounced destructive and inflammatory changes in urothelium characterized by the formation of superficial and deep erosions as well as by association of erosive/destructive damages to the urothelium with proliferative and metaplastic changes. Combined treatment of chronic cystitides and adenomyosis eliminated the destructive and inflammatory alterations in the vesical mucosa in 70 and 93% female patients, respectively (the corresponding values after basic therapy were 60 and 77%), and pronouncedly ameliorated pain syndrome. Springer Science+Business Media New York, 2015 chronic pelvic pain syndrome nationallicence chronic cystitis nationallicence adenomyosis nationallicence pathomorphology nationallicence Shelkovnikova N. Altai State Medical University, Ministry of Health of the Russian Federation, Barnaul, Russia aut Lushnikova E. Research Institute of Regional Pathology and Pathomorphology, Siberian Division of the Russian Academy of Sciences, Novosibirsk, Russia aut Pichigina A. Research Institute of Regional Pathology and Pathomorphology, Siberian Division of the Russian Academy of Sciences, Novosibirsk, Russia aut Neimark A. Altai State Medical University, Ministry of Health of the Russian Federation, Barnaul, Russia aut Bulletin of Experimental Biology and Medicine Springer US; http://www.springer-ny.com 158/6(2015-04-01), 742-747 0007-4888 158:6<742 2015 158 10517 https://doi.org/10.1007/s10517-015-2852-6 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s10517-015-2852-6 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Shelkovnikova N. Altai State Medical University, Ministry of Health of the Russian Federation, Barnaul, Russia aut NATIONALLICENCE 700 1- Lushnikova E. Research Institute of Regional Pathology and Pathomorphology, Siberian Division of the Russian Academy of Sciences, Novosibirsk, Russia aut NATIONALLICENCE 700 1- Pichigina A. Research Institute of Regional Pathology and Pathomorphology, Siberian Division of the Russian Academy of Sciences, Novosibirsk, Russia aut NATIONALLICENCE 700 1- Neimark A. Altai State Medical University, Ministry of Health of the Russian Federation, Barnaul, Russia aut NATIONALLICENCE 773 0- Bulletin of Experimental Biology and Medicine Springer US; http://www.springer-ny.com 158/6(2015-04-01), 742-747 0007-4888 158:6<742 2015 158 10517