New Biomolecular Approaches to the Treatment of Glioblastoma Multiforme
| LEADER | caa a22 4500 | ||
|---|---|---|---|
| 001 | 605537615 | ||
| 003 | CHVBK | ||
| 005 | 20210128100858.0 | ||
| 007 | cr unu---uuuuu | ||
| 008 | 210128e20150401xx s 000 0 eng | ||
| 024 | 7 | 0 | |a 10.1007/s10517-015-2864-2 |2 doi |
| 035 | |a (NATIONALLICENCE)springer-10.1007/s10517-015-2864-2 | ||
| 245 | 0 | 0 | |a New Biomolecular Approaches to the Treatment of Glioblastoma Multiforme |h [Elektronische Daten] |c [I. Bryukhovetskii, A. Bryukhovetskii, Yu. Khotimchenko] |
| 520 | 3 | |a The mechanisms of therapeutic resistance of human glioblastoma multiforme are analyzed. The authors make an attempt at systematization and scientifi c theoretical validation of new approaches to creation of biomedical cellular preparations, based on the oncoproteomic technologies, for personifi ed therapy of the glial tumors. A new approach to the treatment of glioblastoma multiforme with due consideration for the molecular biological characteristics of the tumor stem cells is suggested. It is shown that the tumor stem cell proteome can be regarded as the main target for cell therapy. | |
| 540 | |a Springer Science+Business Media New York, 2015 | ||
| 690 | 7 | |a glioblastoma multiforme |2 nationallicence | |
| 690 | 7 | |a stem cells |2 nationallicence | |
| 690 | 7 | |a genomics |2 nationallicence | |
| 690 | 7 | |a proteomics |2 nationallicence | |
| 690 | 7 | |a transcriptomics |2 nationallicence | |
| 700 | 1 | |a Bryukhovetskii |D I. |u School of Biomedicine, Far-Eastern Federal University, Vladivostok, Russia |4 aut | |
| 700 | 1 | |a Bryukhovetskii |D A. |u School of Biomedicine, Far-Eastern Federal University, Vladivostok, Russia |4 aut | |
| 700 | 1 | |a Khotimchenko |D Yu |u School of Biomedicine, Far-Eastern Federal University, Vladivostok, Russia |4 aut | |
| 773 | 0 | |t Bulletin of Experimental Biology and Medicine |d Springer US; http://www.springer-ny.com |g 158/6(2015-04-01), 794-799 |x 0007-4888 |q 158:6<794 |1 2015 |2 158 |o 10517 | |
| 856 | 4 | 0 | |u https://doi.org/10.1007/s10517-015-2864-2 |q text/html |z Onlinezugriff via DOI |
| 898 | |a BK010053 |b XK010053 |c XK010000 | ||
| 900 | 7 | |a Metadata rights reserved |b Springer special CC-BY-NC licence |2 nationallicence | |
| 908 | |D 1 |a research-article |2 jats | ||
| 949 | |B NATIONALLICENCE |F NATIONALLICENCE |b NL-springer | ||
| 950 | |B NATIONALLICENCE |P 856 |E 40 |u https://doi.org/10.1007/s10517-015-2864-2 |q text/html |z Onlinezugriff via DOI | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Bryukhovetskii |D I. |u School of Biomedicine, Far-Eastern Federal University, Vladivostok, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Bryukhovetskii |D A. |u School of Biomedicine, Far-Eastern Federal University, Vladivostok, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Khotimchenko |D Yu |u School of Biomedicine, Far-Eastern Federal University, Vladivostok, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 773 |E 0- |t Bulletin of Experimental Biology and Medicine |d Springer US; http://www.springer-ny.com |g 158/6(2015-04-01), 794-799 |x 0007-4888 |q 158:6<794 |1 2015 |2 158 |o 10517 | ||