caa a22 4500 605537623 CHVBK 20210128100858.0 cr unu---uuuuu 210128e20150401xx s 000 0 eng 10.1007/s10517-015-2851-7 doi (NATIONALLICENCE)springer-10.1007/s10517-015-2851-7 Cardioprotective Activity of Ganoderma lucidum Extract during Total Ischemia and Reperfusion of Isolated Heart [Elektronische Daten] [T. Lasukova, L. Maslov, A. Arbuzov, V. Burkova, L. Inisheva] The cardioprotective effects of Ganoderma lucidum extract were examined in experiments with global ischemia (45 min) and reperfusion (30 min) of isolated and perfused rat heart. The course of preventive administration of the extract in a dose of 400 mg/kg for 15 days diminished necrotic death of cardiomyocytes and reduced reperfusion contracture. Ganoderma lucidum extract demonstrated antioxidant properties. The authors believe that the cardioprotective properties of Ganoderma lucidum extract are largely determined by its antioxidant properties. Springer Science+Business Media New York, 2015 Ganoderma lucidum nationallicence antioxidants nationallicence heart nationallicence ischemia nationallicence Lasukova T. 1Department of Biomedical Science, Tomsk State Pedagogical University, Tomsk, Russia aut Maslov L. Research Institute of Cardiology, Siberian Division of the Russian Academy of Medical Sciences, Tomsk, Russia aut Arbuzov A. Research Institute of Cardiology, Siberian Division of the Russian Academy of Medical Sciences, Tomsk, Russia aut Burkova V. Research Institute of Cardiology, Siberian Division of the Russian Academy of Medical Sciences, Tomsk, Russia aut Inisheva L. Testing Laboratory of Agroecology, Tomsk State Pedagogical University, Tomsk, Russia aut Bulletin of Experimental Biology and Medicine Springer US; http://www.springer-ny.com 158/6(2015-04-01), 739-741 0007-4888 158:6<739 2015 158 10517 https://doi.org/10.1007/s10517-015-2851-7 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s10517-015-2851-7 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Lasukova T. 1Department of Biomedical Science, Tomsk State Pedagogical University, Tomsk, Russia aut NATIONALLICENCE 700 1- Maslov L. Research Institute of Cardiology, Siberian Division of the Russian Academy of Medical Sciences, Tomsk, Russia aut NATIONALLICENCE 700 1- Arbuzov A. Research Institute of Cardiology, Siberian Division of the Russian Academy of Medical Sciences, Tomsk, Russia aut NATIONALLICENCE 700 1- Burkova V. Research Institute of Cardiology, Siberian Division of the Russian Academy of Medical Sciences, Tomsk, Russia aut NATIONALLICENCE 700 1- Inisheva L. Testing Laboratory of Agroecology, Tomsk State Pedagogical University, Tomsk, Russia aut NATIONALLICENCE 773 0- Bulletin of Experimental Biology and Medicine Springer US; http://www.springer-ny.com 158/6(2015-04-01), 739-741 0007-4888 158:6<739 2015 158 10517