CCL19/CCL21-Dependent Chemotaxis of Dendritic Cells in Healthy Individuals and Patients with Brain Tumors
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| 024 | 7 | 0 | |a 10.1007/s10517-015-2862-4 |2 doi |
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| 245 | 0 | 0 | |a CCL19/CCL21-Dependent Chemotaxis of Dendritic Cells in Healthy Individuals and Patients with Brain Tumors |h [Elektronische Daten] |c [T. Tyrinova, O. Leplina, M. Tikhonova, S. Mishinov, V. Stupak, A. Ostanin, E. Chernykh] |
| 520 | 3 | |a We compared migration activities of IFN-α- and IL-4-induced dendritic cells (IFN-DC and IL4-DC) generated from blood monocytes of healthy donors and analyzed migration activity of IFN-DC from patients with brain tumors. In the presence of CCL19 chemokine, donor IFN-DC exhibited higher migration activity than IL4-DC, the expression of chemokine CCR7-receptor being similar in the two cell types. IFN-DC of patients with malignant gliomas were characterized by low chemotaxis in response to CCL19 and CCL21 stimulation despite a trend to higher expression of CCR7 in comparison with donor IFN-DC. | |
| 540 | |a Springer Science+Business Media New York, 2015 | ||
| 690 | 7 | |a dendritic cells |2 nationallicence | |
| 690 | 7 | |a CCR7 |2 nationallicence | |
| 690 | 7 | |a lymphoid chemokines |2 nationallicence | |
| 690 | 7 | |a cerebral malignant gliomas |2 nationallicence | |
| 700 | 1 | |a Tyrinova |D T. |u Research Institute of Clinical Immunology, Siberian Division of the Russian Academy of Medical Sciences, Novosibirsk, Russia |4 aut | |
| 700 | 1 | |a Leplina |D O. |u Research Institute of Clinical Immunology, Siberian Division of the Russian Academy of Medical Sciences, Novosibirsk, Russia |4 aut | |
| 700 | 1 | |a Tikhonova |D M. |u Research Institute of Clinical Immunology, Siberian Division of the Russian Academy of Medical Sciences, Novosibirsk, Russia |4 aut | |
| 700 | 1 | |a Mishinov |D S. |u Research Institute of Traumatology and Orthopedics, Rosmedtechnologies, Novosibirsk, Russia |4 aut | |
| 700 | 1 | |a Stupak |D V. |u Research Institute of Traumatology and Orthopedics, Rosmedtechnologies, Novosibirsk, Russia |4 aut | |
| 700 | 1 | |a Ostanin |D A. |u Research Institute of Clinical Immunology, Siberian Division of the Russian Academy of Medical Sciences, Novosibirsk, Russia |4 aut | |
| 700 | 1 | |a Chernykh |D E. |u Research Institute of Clinical Immunology, Siberian Division of the Russian Academy of Medical Sciences, Novosibirsk, Russia |4 aut | |
| 773 | 0 | |t Bulletin of Experimental Biology and Medicine |d Springer US; http://www.springer-ny.com |g 158/6(2015-04-01), 785-788 |x 0007-4888 |q 158:6<785 |1 2015 |2 158 |o 10517 | |
| 856 | 4 | 0 | |u https://doi.org/10.1007/s10517-015-2862-4 |q text/html |z Onlinezugriff via DOI |
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| 900 | 7 | |a Metadata rights reserved |b Springer special CC-BY-NC licence |2 nationallicence | |
| 908 | |D 1 |a research-article |2 jats | ||
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| 950 | |B NATIONALLICENCE |P 856 |E 40 |u https://doi.org/10.1007/s10517-015-2862-4 |q text/html |z Onlinezugriff via DOI | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Tyrinova |D T. |u Research Institute of Clinical Immunology, Siberian Division of the Russian Academy of Medical Sciences, Novosibirsk, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Leplina |D O. |u Research Institute of Clinical Immunology, Siberian Division of the Russian Academy of Medical Sciences, Novosibirsk, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Tikhonova |D M. |u Research Institute of Clinical Immunology, Siberian Division of the Russian Academy of Medical Sciences, Novosibirsk, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Mishinov |D S. |u Research Institute of Traumatology and Orthopedics, Rosmedtechnologies, Novosibirsk, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Stupak |D V. |u Research Institute of Traumatology and Orthopedics, Rosmedtechnologies, Novosibirsk, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Ostanin |D A. |u Research Institute of Clinical Immunology, Siberian Division of the Russian Academy of Medical Sciences, Novosibirsk, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Chernykh |D E. |u Research Institute of Clinical Immunology, Siberian Division of the Russian Academy of Medical Sciences, Novosibirsk, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 773 |E 0- |t Bulletin of Experimental Biology and Medicine |d Springer US; http://www.springer-ny.com |g 158/6(2015-04-01), 785-788 |x 0007-4888 |q 158:6<785 |1 2015 |2 158 |o 10517 | ||