Effects of Iron Ions and Iron Chelation on the Efficiency of Experimental Radiotherapy of Animals with Gliomas

Verfasser / Beitragende:
[S. Ivanov, A. Semenov, E. Kovan'ko, V. Yamshanov]
Ort, Verlag, Jahr:
2015
Enthalten in:
Bulletin of Experimental Biology and Medicine, 158/6(2015-04-01), 800-803
Format:
Artikel (online)
ID: 605537658
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024 7 0 |a 10.1007/s10517-015-2865-1  |2 doi 
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245 0 0 |a Effects of Iron Ions and Iron Chelation on the Efficiency of Experimental Radiotherapy of Animals with Gliomas  |h [Elektronische Daten]  |c [S. Ivanov, A. Semenov, E. Kovan'ko, V. Yamshanov] 
520 3 |a We evaluated the effect of iron ion chelation on the growth of gliomas and radiotherapy efficiency in tumor-bearing animals. The rats with transplanted glioma-35 received iron-containing water; desferroxamine was injected for metal chelation. Long-term treatment with iron-containing water promoted glioma growth in rats and improved the efficiency of radiotherapy due to combination of apoptosis and ferroptosis. Desferroxamine reduced the efficiency of this treatment and was inessential for the efficiency of radiotherapy alone. 
540 |a Springer Science+Business Media New York, 2015 
690 7 |a rats  |2 nationallicence 
690 7 |a gliomas  |2 nationallicence 
690 7 |a radiotherapy  |2 nationallicence 
690 7 |a iron ions  |2 nationallicence 
690 7 |a desferroxamine  |2 nationallicence 
700 1 |a Ivanov  |D S.  |u Russian Research Center of Radiology and Surgical Technologies, Ministry of Health of the Russian Federation, St. Petersburg, Russia  |4 aut 
700 1 |a Semenov  |D A.  |u Russian Research Center of Radiology and Surgical Technologies, Ministry of Health of the Russian Federation, St. Petersburg, Russia  |4 aut 
700 1 |a Kovan'ko  |D E.  |u Russian Research Center of Radiology and Surgical Technologies, Ministry of Health of the Russian Federation, St. Petersburg, Russia  |4 aut 
700 1 |a Yamshanov  |D V.  |u Russian Research Center of Radiology and Surgical Technologies, Ministry of Health of the Russian Federation, St. Petersburg, Russia  |4 aut 
773 0 |t Bulletin of Experimental Biology and Medicine  |d Springer US; http://www.springer-ny.com  |g 158/6(2015-04-01), 800-803  |x 0007-4888  |q 158:6<800  |1 2015  |2 158  |o 10517 
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950 |B NATIONALLICENCE  |P 700  |E 1-  |a Ivanov  |D S.  |u Russian Research Center of Radiology and Surgical Technologies, Ministry of Health of the Russian Federation, St. Petersburg, Russia  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Semenov  |D A.  |u Russian Research Center of Radiology and Surgical Technologies, Ministry of Health of the Russian Federation, St. Petersburg, Russia  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Kovan'ko  |D E.  |u Russian Research Center of Radiology and Surgical Technologies, Ministry of Health of the Russian Federation, St. Petersburg, Russia  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Yamshanov  |D V.  |u Russian Research Center of Radiology and Surgical Technologies, Ministry of Health of the Russian Federation, St. Petersburg, Russia  |4 aut 
950 |B NATIONALLICENCE  |P 773  |E 0-  |t Bulletin of Experimental Biology and Medicine  |d Springer US; http://www.springer-ny.com  |g 158/6(2015-04-01), 800-803  |x 0007-4888  |q 158:6<800  |1 2015  |2 158  |o 10517