Elimination of Iron-Containing Magnetic Nanoparticles from the Site of Injection in Mice: a Magnetic-Resonance Imaging Study

Verfasser / Beitragende:
[E. Inzhevatkin, E. Morozov, E. Khilazheva, V. Ladygina, S. Stolyar, O. Falaleev]
Ort, Verlag, Jahr:
2015
Enthalten in:
Bulletin of Experimental Biology and Medicine, 158/6(2015-04-01), 807-811
Format:
Artikel (online)
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024 7 0 |a 10.1007/s10517-015-2867-z  |2 doi 
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245 0 0 |a Elimination of Iron-Containing Magnetic Nanoparticles from the Site of Injection in Mice: a Magnetic-Resonance Imaging Study  |h [Elektronische Daten]  |c [E. Inzhevatkin, E. Morozov, E. Khilazheva, V. Ladygina, S. Stolyar, O. Falaleev] 
520 3 |a Suspension of magnetic nanoparticles (0.7 g/liter) obtained from Klebsiella oxytoca culture was injected intraperitoneally (1 ml), intramuscularly (in the hip; 100 μl), and subcutaneously (200 μl) or administered orally instead of drinking water for 2 days. The presence of magnetic nanoparticles was evaluated detected by MRI in 15 min and 2 h after injections and in 1 and 2 days after the beginning of oral consumption of the suspension. Magnetic nanoparticles were eliminated from the site of intramuscular and intraperitoneal injections and after oral consumption. The period of elimination after intramuscular and intraperitoneal injections did not exceed 2 h, while after oral consumption it corresponded to the time of gastrointestinal tract contents evacuation. 
540 |a Springer Science+Business Media New York, 2015 
690 7 |a magnetic nanoparticles  |2 nationallicence 
690 7 |a Klebsiella oxytoca  |2 nationallicence 
690 7 |a magnetic resonance imaging  |2 nationallicence 
690 7 |a elimination  |2 nationallicence 
700 1 |a Inzhevatkin  |D E.  |u Krasnoyarsk Research Center, Siberian Division of the Russian Academy of Sciences, Krasnoyarsk, Russia  |4 aut 
700 1 |a Morozov  |D E.  |u L. V. Kirensky Institute of Physics, Krasnoyarsk, Russia  |4 aut 
700 1 |a Khilazheva  |D E.  |u Siberian Federal University, Krasnoyarsk, Russia  |4 aut 
700 1 |a Ladygina  |D V.  |u Krasnoyarsk Research Center, Siberian Division of the Russian Academy of Sciences, Krasnoyarsk, Russia  |4 aut 
700 1 |a Stolyar  |D S.  |u L. V. Kirensky Institute of Physics, Krasnoyarsk, Russia  |4 aut 
700 1 |a Falaleev  |D O.  |u Krasnoyarsk Research Center, Siberian Division of the Russian Academy of Sciences, Krasnoyarsk, Russia  |4 aut 
773 0 |t Bulletin of Experimental Biology and Medicine  |d Springer US; http://www.springer-ny.com  |g 158/6(2015-04-01), 807-811  |x 0007-4888  |q 158:6<807  |1 2015  |2 158  |o 10517 
856 4 0 |u https://doi.org/10.1007/s10517-015-2867-z  |q text/html  |z Onlinezugriff via DOI 
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950 |B NATIONALLICENCE  |P 700  |E 1-  |a Inzhevatkin  |D E.  |u Krasnoyarsk Research Center, Siberian Division of the Russian Academy of Sciences, Krasnoyarsk, Russia  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Morozov  |D E.  |u L. V. Kirensky Institute of Physics, Krasnoyarsk, Russia  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Khilazheva  |D E.  |u Siberian Federal University, Krasnoyarsk, Russia  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Ladygina  |D V.  |u Krasnoyarsk Research Center, Siberian Division of the Russian Academy of Sciences, Krasnoyarsk, Russia  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Stolyar  |D S.  |u L. V. Kirensky Institute of Physics, Krasnoyarsk, Russia  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Falaleev  |D O.  |u Krasnoyarsk Research Center, Siberian Division of the Russian Academy of Sciences, Krasnoyarsk, Russia  |4 aut 
950 |B NATIONALLICENCE  |P 773  |E 0-  |t Bulletin of Experimental Biology and Medicine  |d Springer US; http://www.springer-ny.com  |g 158/6(2015-04-01), 807-811  |x 0007-4888  |q 158:6<807  |1 2015  |2 158  |o 10517