caa a22 4500 605537712 CHVBK 20210128100858.0 cr unu---uuuuu 210128e20150401xx s 000 0 eng 10.1007/s10517-015-2867-z doi (NATIONALLICENCE)springer-10.1007/s10517-015-2867-z Elimination of Iron-Containing Magnetic Nanoparticles from the Site of Injection in Mice: a Magnetic-Resonance Imaging Study [Elektronische Daten] [E. Inzhevatkin, E. Morozov, E. Khilazheva, V. Ladygina, S. Stolyar, O. Falaleev] Suspension of magnetic nanoparticles (0.7 g/liter) obtained from Klebsiella oxytoca culture was injected intraperitoneally (1 ml), intramuscularly (in the hip; 100 μl), and subcutaneously (200 μl) or administered orally instead of drinking water for 2 days. The presence of magnetic nanoparticles was evaluated detected by MRI in 15 min and 2 h after injections and in 1 and 2 days after the beginning of oral consumption of the suspension. Magnetic nanoparticles were eliminated from the site of intramuscular and intraperitoneal injections and after oral consumption. The period of elimination after intramuscular and intraperitoneal injections did not exceed 2 h, while after oral consumption it corresponded to the time of gastrointestinal tract contents evacuation. Springer Science+Business Media New York, 2015 magnetic nanoparticles nationallicence Klebsiella oxytoca nationallicence magnetic resonance imaging nationallicence elimination nationallicence Inzhevatkin E. Krasnoyarsk Research Center, Siberian Division of the Russian Academy of Sciences, Krasnoyarsk, Russia aut Morozov E. L. V. Kirensky Institute of Physics, Krasnoyarsk, Russia aut Khilazheva E. Siberian Federal University, Krasnoyarsk, Russia aut Ladygina V. Krasnoyarsk Research Center, Siberian Division of the Russian Academy of Sciences, Krasnoyarsk, Russia aut Stolyar S. L. V. Kirensky Institute of Physics, Krasnoyarsk, Russia aut Falaleev O. Krasnoyarsk Research Center, Siberian Division of the Russian Academy of Sciences, Krasnoyarsk, Russia aut Bulletin of Experimental Biology and Medicine Springer US; http://www.springer-ny.com 158/6(2015-04-01), 807-811 0007-4888 158:6<807 2015 158 10517 https://doi.org/10.1007/s10517-015-2867-z text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s10517-015-2867-z text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Inzhevatkin E. Krasnoyarsk Research Center, Siberian Division of the Russian Academy of Sciences, Krasnoyarsk, Russia aut NATIONALLICENCE 700 1- Morozov E. L. V. Kirensky Institute of Physics, Krasnoyarsk, Russia aut NATIONALLICENCE 700 1- Khilazheva E. Siberian Federal University, Krasnoyarsk, Russia aut NATIONALLICENCE 700 1- Ladygina V. Krasnoyarsk Research Center, Siberian Division of the Russian Academy of Sciences, Krasnoyarsk, Russia aut NATIONALLICENCE 700 1- Stolyar S. L. V. Kirensky Institute of Physics, Krasnoyarsk, Russia aut NATIONALLICENCE 700 1- Falaleev O. Krasnoyarsk Research Center, Siberian Division of the Russian Academy of Sciences, Krasnoyarsk, Russia aut NATIONALLICENCE 773 0- Bulletin of Experimental Biology and Medicine Springer US; http://www.springer-ny.com 158/6(2015-04-01), 807-811 0007-4888 158:6<807 2015 158 10517