Neuroprotective and Antiamnesic Effect of Erythropoietin Derivatives after Experimental Ischemic Injury of Cerebral Cortex
| LEADER | caa a22 4500 | ||
|---|---|---|---|
| 001 | 605537763 | ||
| 003 | CHVBK | ||
| 005 | 20210128100859.0 | ||
| 007 | cr unu---uuuuu | ||
| 008 | 210128e20150101xx s 000 0 eng | ||
| 024 | 7 | 0 | |a 10.1007/s10517-015-2751-x |2 doi |
| 035 | |a (NATIONALLICENCE)springer-10.1007/s10517-015-2751-x | ||
| 245 | 0 | 0 | |a Neuroprotective and Antiamnesic Effect of Erythropoietin Derivatives after Experimental Ischemic Injury of Cerebral Cortex |h [Elektronische Daten] |c [G. Romanova, F. Shakova, I. Barskov, E. Stel'mashuk, E. Genrikhs, A. Cheremnykh, T. Kalinina, V. Yurin] |
| 520 | 3 | |a Using the model of bilateral photothrombosis of the blood vessels in the prefrontal cortex we have shown that new hybrid proteins derived from recombinant human erythropoietin, carbamylated EPO-Fc and EPO-TR fusion proteins, injected intraperitoneally 1 h after ischemic injury contribute to restoration of passive avoidance response formed before photothrombotic injury and reduction in the volume of the ischemic focus. These data attest to nootropic and neuroprotective activities of these hybrid proteins. Carbamylated glycopeptide derivative ЕPO-TR exhibited prolonged neuroprotective properties. | |
| 540 | |a Springer Science+Business Media New York, 2015 | ||
| 690 | 7 | |a hybrid proteins of erythropoietin |2 nationallicence | |
| 690 | 7 | |a photothrombosis |2 nationallicence | |
| 690 | 7 | |a prefrontal cortex |2 nationallicence | |
| 700 | 1 | |a Romanova |D G. |u Research Institute of General Pathology and Pathophysiology, Russian Academy of Medical Sciences, Moscow, Russia |4 aut | |
| 700 | 1 | |a Shakova |D F. |u Research Institute of General Pathology and Pathophysiology, Russian Academy of Medical Sciences, Moscow, Russia |4 aut | |
| 700 | 1 | |a Barskov |D I. |u Research Institute of General Pathology and Pathophysiology, Russian Academy of Medical Sciences, Moscow, Russia |4 aut | |
| 700 | 1 | |a Stel'mashuk |D E. |u Research Center of Neurology, Russian Academy of Medical Sciences, Moscow, Russia |4 aut | |
| 700 | 1 | |a Genrikhs |D E. |u Research Center of Neurology, Russian Academy of Medical Sciences, Moscow, Russia |4 aut | |
| 700 | 1 | |a Cheremnykh |D A. |u State Research Institute of Genetics and Selection of Industrial Microorganisms, Moscow, Russia |4 aut | |
| 700 | 1 | |a Kalinina |D T. |u State Research Institute of Genetics and Selection of Industrial Microorganisms, Moscow, Russia |4 aut | |
| 700 | 1 | |a Yurin |D V. |u State Research Institute of Genetics and Selection of Industrial Microorganisms, Moscow, Russia |4 aut | |
| 773 | 0 | |t Bulletin of Experimental Biology and Medicine |d Springer US; http://www.springer-ny.com |g 158/3(2015-01-01), 318-321 |x 0007-4888 |q 158:3<318 |1 2015 |2 158 |o 10517 | |
| 856 | 4 | 0 | |u https://doi.org/10.1007/s10517-015-2751-x |q text/html |z Onlinezugriff via DOI |
| 898 | |a BK010053 |b XK010053 |c XK010000 | ||
| 900 | 7 | |a Metadata rights reserved |b Springer special CC-BY-NC licence |2 nationallicence | |
| 908 | |D 1 |a research-article |2 jats | ||
| 949 | |B NATIONALLICENCE |F NATIONALLICENCE |b NL-springer | ||
| 950 | |B NATIONALLICENCE |P 856 |E 40 |u https://doi.org/10.1007/s10517-015-2751-x |q text/html |z Onlinezugriff via DOI | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Romanova |D G. |u Research Institute of General Pathology and Pathophysiology, Russian Academy of Medical Sciences, Moscow, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Shakova |D F. |u Research Institute of General Pathology and Pathophysiology, Russian Academy of Medical Sciences, Moscow, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Barskov |D I. |u Research Institute of General Pathology and Pathophysiology, Russian Academy of Medical Sciences, Moscow, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Stel'mashuk |D E. |u Research Center of Neurology, Russian Academy of Medical Sciences, Moscow, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Genrikhs |D E. |u Research Center of Neurology, Russian Academy of Medical Sciences, Moscow, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Cheremnykh |D A. |u State Research Institute of Genetics and Selection of Industrial Microorganisms, Moscow, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Kalinina |D T. |u State Research Institute of Genetics and Selection of Industrial Microorganisms, Moscow, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Yurin |D V. |u State Research Institute of Genetics and Selection of Industrial Microorganisms, Moscow, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 773 |E 0- |t Bulletin of Experimental Biology and Medicine |d Springer US; http://www.springer-ny.com |g 158/3(2015-01-01), 318-321 |x 0007-4888 |q 158:3<318 |1 2015 |2 158 |o 10517 | ||