Nootropic Dipeptide Noopept Enhances Inhibitory Synaptic Transmission in the Hippocampus
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| 024 | 7 | 0 | |a 10.1007/s10517-015-2759-2 |2 doi |
| 035 | |a (NATIONALLICENCE)springer-10.1007/s10517-015-2759-2 | ||
| 245 | 0 | 0 | |a Nootropic Dipeptide Noopept Enhances Inhibitory Synaptic Transmission in the Hippocampus |h [Elektronische Daten] |c [I. Povarov, R. Kondratenko, V. Derevyagin, R. Ostrovskaya, V. Skrebitskii] |
| 520 | 3 | |a Application of nootropic agent Noopept on hippocampal slices from Wistar rats enhanced the inhibitory component of total current induced by stimulation of Shaffer collaterals in CA1 pyramidal neurons, but did not affect the excitatory component. A direct correlation between the increase in the amplitude of inhibitory current and agent concentration was found. The substance did not affect the release of inhibitory transmitters from terminals in the pyramidal neurons, which indicated changes in GABAergic interneurons. | |
| 540 | |a Springer Science+Business Media New York, 2015 | ||
| 690 | 7 | |a hippocampal slices |2 nationallicence | |
| 690 | 7 | |a patch-clamp |2 nationallicence | |
| 690 | 7 | |a Shaffer collaterals |2 nationallicence | |
| 690 | 7 | |a Noopept |2 nationallicence | |
| 690 | 7 | |a inhibitory interneurons |2 nationallicence | |
| 700 | 1 | |a Povarov |D I. |u Scientific Center for Neurology, Russian Academy of Medical Sciences, Moscow, Russia |4 aut | |
| 700 | 1 | |a Kondratenko |D R. |u Scientific Center for Neurology, Russian Academy of Medical Sciences, Moscow, Russia |4 aut | |
| 700 | 1 | |a Derevyagin |D V. |u Scientific Center for Neurology, Russian Academy of Medical Sciences, Moscow, Russia |4 aut | |
| 700 | 1 | |a Ostrovskaya |D R. |u Institute of Pharmacology, Russian Academy of Medical Sciences, Moscow, Russia |4 aut | |
| 700 | 1 | |a Skrebitskii |D V. |u Scientific Center for Neurology, Russian Academy of Medical Sciences, Moscow, Russia |4 aut | |
| 773 | 0 | |t Bulletin of Experimental Biology and Medicine |d Springer US; http://www.springer-ny.com |g 158/3(2015-01-01), 349-351 |x 0007-4888 |q 158:3<349 |1 2015 |2 158 |o 10517 | |
| 856 | 4 | 0 | |u https://doi.org/10.1007/s10517-015-2759-2 |q text/html |z Onlinezugriff via DOI |
| 898 | |a BK010053 |b XK010053 |c XK010000 | ||
| 900 | 7 | |a Metadata rights reserved |b Springer special CC-BY-NC licence |2 nationallicence | |
| 908 | |D 1 |a research-article |2 jats | ||
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| 950 | |B NATIONALLICENCE |P 856 |E 40 |u https://doi.org/10.1007/s10517-015-2759-2 |q text/html |z Onlinezugriff via DOI | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Povarov |D I. |u Scientific Center for Neurology, Russian Academy of Medical Sciences, Moscow, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Kondratenko |D R. |u Scientific Center for Neurology, Russian Academy of Medical Sciences, Moscow, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Derevyagin |D V. |u Scientific Center for Neurology, Russian Academy of Medical Sciences, Moscow, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Ostrovskaya |D R. |u Institute of Pharmacology, Russian Academy of Medical Sciences, Moscow, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Skrebitskii |D V. |u Scientific Center for Neurology, Russian Academy of Medical Sciences, Moscow, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 773 |E 0- |t Bulletin of Experimental Biology and Medicine |d Springer US; http://www.springer-ny.com |g 158/3(2015-01-01), 349-351 |x 0007-4888 |q 158:3<349 |1 2015 |2 158 |o 10517 | ||