Effects of β-Endorphin on Functional Activity of Mouse Splenocytes under Conditions of In Vivo Blockade of μ,δ-Opioid Receptors
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| 024 | 7 | 0 | |a 10.1007/s10517-015-2761-8 |2 doi |
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| 245 | 0 | 0 | |a Effects of β-Endorphin on Functional Activity of Mouse Splenocytes under Conditions of In Vivo Blockade of μ,δ-Opioid Receptors |h [Elektronische Daten] |c [S. Gein, T. Baeva, V. Nebogatikov] |
| 520 | 3 | |a Blockade of δ-receptors with naltrindole under conditions of systemic immunization abolished the stimulatory effect of β-endorphin (0.0005 μg/kg) on the counts of antibody-producing cells and the titer of antierythrocyte antibodies. Injection of β-endorphin to mice led to stimulation of concanavalin A-induced proliferative activity of splenocytes and IL-4 secretion by the naloxone-dependent mechanism. The peptide did not modify the production of IL-2 and IFN-γ. | |
| 540 | |a Springer Science+Business Media New York, 2015 | ||
| 690 | 7 | |a β-endorphin |2 nationallicence | |
| 690 | 7 | |a opioid receptors |2 nationallicence | |
| 690 | 7 | |a cytokines |2 nationallicence | |
| 690 | 7 | |a antibody production |2 nationallicence | |
| 700 | 1 | |a Gein |D S. |u Institute of Ecology and Genetics of Microorganisms, Ural Division of the Russian Academy of Sciences, Perm, Russia |4 aut | |
| 700 | 1 | |a Baeva |D T. |u Institute of Ecology and Genetics of Microorganisms, Ural Division of the Russian Academy of Sciences, Perm, Russia |4 aut | |
| 700 | 1 | |a Nebogatikov |D V. |u Perm State University, Perm, Russia |4 aut | |
| 773 | 0 | |t Bulletin of Experimental Biology and Medicine |d Springer US; http://www.springer-ny.com |g 158/3(2015-01-01), 356-360 |x 0007-4888 |q 158:3<356 |1 2015 |2 158 |o 10517 | |
| 856 | 4 | 0 | |u https://doi.org/10.1007/s10517-015-2761-8 |q text/html |z Onlinezugriff via DOI |
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| 908 | |D 1 |a research-article |2 jats | ||
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| 950 | |B NATIONALLICENCE |P 856 |E 40 |u https://doi.org/10.1007/s10517-015-2761-8 |q text/html |z Onlinezugriff via DOI | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Gein |D S. |u Institute of Ecology and Genetics of Microorganisms, Ural Division of the Russian Academy of Sciences, Perm, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Baeva |D T. |u Institute of Ecology and Genetics of Microorganisms, Ural Division of the Russian Academy of Sciences, Perm, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Nebogatikov |D V. |u Perm State University, Perm, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 773 |E 0- |t Bulletin of Experimental Biology and Medicine |d Springer US; http://www.springer-ny.com |g 158/3(2015-01-01), 356-360 |x 0007-4888 |q 158:3<356 |1 2015 |2 158 |o 10517 | ||