Ca2+ Ions Regulate Activity of Na+,Cl-(HCO 3 − )-ATPase in the Mucosa of Rabbit Small Intestine
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| 024 | 7 | 0 | |a 10.1007/s10517-015-2753-8 |2 doi |
| 035 | |a (NATIONALLICENCE)springer-10.1007/s10517-015-2753-8 | ||
| 245 | 0 | 0 | |a Ca2+ Ions Regulate Activity of Na+,Cl-(HCO 3 − )-ATPase in the Mucosa of Rabbit Small Intestine |h [Elektronische Daten] |c [V. Yurkiv, V. Melikhov, V. Shubin] |
| 520 | 3 | |a We studied the effects of bivalent metal ions on activity of Na+,Cl-(HCO3 -)-ATPase was studied. In contrast to Ba2+, Co2+, Zn2+, and Mn2+ ions, Ca2+ and Mg2+ ions in a concentration of 0.25 mM completely inhibited this enzyme. Histamine in vivo significantly decreased the inhibiting effect of Ca2+ on Na+,Cl-(HCO3 -)-ATPase. A possible mechanism of regulation of enzyme activity by Ca2+ ions and its possible relation with CFTR protein providing permeability of enterocyte apical membrane for Cl- ions was proposed. | |
| 540 | |a Springer Science+Business Media New York, 2015 | ||
| 690 | 7 | |a secretory process |2 nationallicence | |
| 690 | 7 | |a small intestine |2 nationallicence | |
| 690 | 7 | |a transport ATPase |2 nationallicence | |
| 690 | 7 | |a CFTR |2 nationallicence | |
| 700 | 1 | |a Yurkiv |D V. |u Laboratory of Molecular Mechanisms for Infections, Central Research Institute of Epidemiology, Moscow, Russia |4 aut | |
| 700 | 1 | |a Melikhov |D V. |u Laboratory of Molecular Mechanisms for Infections, Central Research Institute of Epidemiology, Moscow, Russia |4 aut | |
| 700 | 1 | |a Shubin |D V. |u Laboratory of Molecular Mechanisms for Infections, Central Research Institute of Epidemiology, Moscow, Russia |4 aut | |
| 773 | 0 | |t Bulletin of Experimental Biology and Medicine |d Springer US; http://www.springer-ny.com |g 158/3(2015-01-01), 326-328 |x 0007-4888 |q 158:3<326 |1 2015 |2 158 |o 10517 | |
| 856 | 4 | 0 | |u https://doi.org/10.1007/s10517-015-2753-8 |q text/html |z Onlinezugriff via DOI |
| 898 | |a BK010053 |b XK010053 |c XK010000 | ||
| 900 | 7 | |a Metadata rights reserved |b Springer special CC-BY-NC licence |2 nationallicence | |
| 908 | |D 1 |a research-article |2 jats | ||
| 949 | |B NATIONALLICENCE |F NATIONALLICENCE |b NL-springer | ||
| 950 | |B NATIONALLICENCE |P 856 |E 40 |u https://doi.org/10.1007/s10517-015-2753-8 |q text/html |z Onlinezugriff via DOI | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Yurkiv |D V. |u Laboratory of Molecular Mechanisms for Infections, Central Research Institute of Epidemiology, Moscow, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Melikhov |D V. |u Laboratory of Molecular Mechanisms for Infections, Central Research Institute of Epidemiology, Moscow, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Shubin |D V. |u Laboratory of Molecular Mechanisms for Infections, Central Research Institute of Epidemiology, Moscow, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 773 |E 0- |t Bulletin of Experimental Biology and Medicine |d Springer US; http://www.springer-ny.com |g 158/3(2015-01-01), 326-328 |x 0007-4888 |q 158:3<326 |1 2015 |2 158 |o 10517 | ||