Cerebroprotective and Regenerative Effects of Alkaloid Z77 under Conditions of Brain Ischemia
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| 024 | 7 | 0 | |a 10.1007/s10517-015-2760-9 |2 doi |
| 035 | |a (NATIONALLICENCE)springer-10.1007/s10517-015-2760-9 | ||
| 245 | 0 | 0 | |a Cerebroprotective and Regenerative Effects of Alkaloid Z77 under Conditions of Brain Ischemia |h [Elektronische Daten] |c [G. Zyuz'kov, N. Suslov, E. Losev, L. Ermolaeva, V. Zhdanov, E. Udut, L. Miroshnichenko, E. Simanina, V. Demkin, T. Povet'eva, Yu. Nesterova, V. Udut, M. Minakova, A. Dygai] |
| 520 | 3 | |a We studied the psychopharmacological effects of atisine-type diterpene alkaloid Z77 in a rat model of cerebral ischemia. Pronounced cerebroprotective effect was found consisting in normalization of the orienting and exploratory activity and conditioned behavior associated with significant correction of morphological changes in the brain. The direct stimulatory effect of Z77 on neural stem cells was shown in vitro. | |
| 540 | |a Springer Science+Business Media New York, 2015 | ||
| 690 | 7 | |a regenerative medicine |2 nationallicence | |
| 690 | 7 | |a cerebroprotective drugs |2 nationallicence | |
| 690 | 7 | |a alkaloids |2 nationallicence | |
| 690 | 7 | |a neural stem cells |2 nationallicence | |
| 690 | 7 | |a cerebral ischemia |2 nationallicence | |
| 700 | 1 | |a Zyuz'kov |D G. |u E. D. Goldberg Research Institute of Pharmacology, Siberian Division of the Russian Academy of Medical Sciences, Tomsk, Russia |4 aut | |
| 700 | 1 | |a Suslov |D N. |u E. D. Goldberg Research Institute of Pharmacology, Siberian Division of the Russian Academy of Medical Sciences, Tomsk, Russia |4 aut | |
| 700 | 1 | |a Losev |D E. |u E. D. Goldberg Research Institute of Pharmacology, Siberian Division of the Russian Academy of Medical Sciences, Tomsk, Russia |4 aut | |
| 700 | 1 | |a Ermolaeva |D L. |u E. D. Goldberg Research Institute of Pharmacology, Siberian Division of the Russian Academy of Medical Sciences, Tomsk, Russia |4 aut | |
| 700 | 1 | |a Zhdanov |D V. |u E. D. Goldberg Research Institute of Pharmacology, Siberian Division of the Russian Academy of Medical Sciences, Tomsk, Russia |4 aut | |
| 700 | 1 | |a Udut |D E. |u E. D. Goldberg Research Institute of Pharmacology, Siberian Division of the Russian Academy of Medical Sciences, Tomsk, Russia |4 aut | |
| 700 | 1 | |a Miroshnichenko |D L. |u E. D. Goldberg Research Institute of Pharmacology, Siberian Division of the Russian Academy of Medical Sciences, Tomsk, Russia |4 aut | |
| 700 | 1 | |a Simanina |D E. |u E. D. Goldberg Research Institute of Pharmacology, Siberian Division of the Russian Academy of Medical Sciences, Tomsk, Russia |4 aut | |
| 700 | 1 | |a Demkin |D V. |u National Research Tomsk State University, Tomsk, Russia |4 aut | |
| 700 | 1 | |a Povet'eva |D T. |u E. D. Goldberg Research Institute of Pharmacology, Siberian Division of the Russian Academy of Medical Sciences, Tomsk, Russia |4 aut | |
| 700 | 1 | |a Nesterova |D Yu |u E. D. Goldberg Research Institute of Pharmacology, Siberian Division of the Russian Academy of Medical Sciences, Tomsk, Russia |4 aut | |
| 700 | 1 | |a Udut |D V. |u E. D. Goldberg Research Institute of Pharmacology, Siberian Division of the Russian Academy of Medical Sciences, Tomsk, Russia |4 aut | |
| 700 | 1 | |a Minakova |D M. |u E. D. Goldberg Research Institute of Pharmacology, Siberian Division of the Russian Academy of Medical Sciences, Tomsk, Russia |4 aut | |
| 700 | 1 | |a Dygai |D A. |u E. D. Goldberg Research Institute of Pharmacology, Siberian Division of the Russian Academy of Medical Sciences, Tomsk, Russia |4 aut | |
| 773 | 0 | |t Bulletin of Experimental Biology and Medicine |d Springer US; http://www.springer-ny.com |g 158/3(2015-01-01), 352-355 |x 0007-4888 |q 158:3<352 |1 2015 |2 158 |o 10517 | |
| 856 | 4 | 0 | |u https://doi.org/10.1007/s10517-015-2760-9 |q text/html |z Onlinezugriff via DOI |
| 898 | |a BK010053 |b XK010053 |c XK010000 | ||
| 900 | 7 | |a Metadata rights reserved |b Springer special CC-BY-NC licence |2 nationallicence | |
| 908 | |D 1 |a research-article |2 jats | ||
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| 950 | |B NATIONALLICENCE |P 856 |E 40 |u https://doi.org/10.1007/s10517-015-2760-9 |q text/html |z Onlinezugriff via DOI | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Zyuz'kov |D G. |u E. D. Goldberg Research Institute of Pharmacology, Siberian Division of the Russian Academy of Medical Sciences, Tomsk, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Suslov |D N. |u E. D. Goldberg Research Institute of Pharmacology, Siberian Division of the Russian Academy of Medical Sciences, Tomsk, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Losev |D E. |u E. D. Goldberg Research Institute of Pharmacology, Siberian Division of the Russian Academy of Medical Sciences, Tomsk, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Ermolaeva |D L. |u E. D. Goldberg Research Institute of Pharmacology, Siberian Division of the Russian Academy of Medical Sciences, Tomsk, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Zhdanov |D V. |u E. D. Goldberg Research Institute of Pharmacology, Siberian Division of the Russian Academy of Medical Sciences, Tomsk, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Udut |D E. |u E. D. Goldberg Research Institute of Pharmacology, Siberian Division of the Russian Academy of Medical Sciences, Tomsk, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Miroshnichenko |D L. |u E. D. Goldberg Research Institute of Pharmacology, Siberian Division of the Russian Academy of Medical Sciences, Tomsk, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Simanina |D E. |u E. D. Goldberg Research Institute of Pharmacology, Siberian Division of the Russian Academy of Medical Sciences, Tomsk, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Demkin |D V. |u National Research Tomsk State University, Tomsk, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Povet'eva |D T. |u E. D. Goldberg Research Institute of Pharmacology, Siberian Division of the Russian Academy of Medical Sciences, Tomsk, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Nesterova |D Yu |u E. D. Goldberg Research Institute of Pharmacology, Siberian Division of the Russian Academy of Medical Sciences, Tomsk, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Udut |D V. |u E. D. Goldberg Research Institute of Pharmacology, Siberian Division of the Russian Academy of Medical Sciences, Tomsk, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Minakova |D M. |u E. D. Goldberg Research Institute of Pharmacology, Siberian Division of the Russian Academy of Medical Sciences, Tomsk, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Dygai |D A. |u E. D. Goldberg Research Institute of Pharmacology, Siberian Division of the Russian Academy of Medical Sciences, Tomsk, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 773 |E 0- |t Bulletin of Experimental Biology and Medicine |d Springer US; http://www.springer-ny.com |g 158/3(2015-01-01), 352-355 |x 0007-4888 |q 158:3<352 |1 2015 |2 158 |o 10517 | ||