P388 Leukemia in CDF1 Mice as the Test System for Studies of Tumor-Associated Neoangiogenesis and Hypercoagulation

Verfasser / Beitragende:
[A. Trashkov, A. Panchenko, E. Kayukova, R. Korablev, V. Pechatnikova, A. Vasil'ev, V. Anisimov]
Ort, Verlag, Jahr:
2015
Enthalten in:
Bulletin of Experimental Biology and Medicine, 158/4(2015-02-01), 497-499
Format:
Artikel (online)
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245 0 0 |a P388 Leukemia in CDF1 Mice as the Test System for Studies of Tumor-Associated Neoangiogenesis and Hypercoagulation  |h [Elektronische Daten]  |c [A. Trashkov, A. Panchenko, E. Kayukova, R. Korablev, V. Pechatnikova, A. Vasil'ev, V. Anisimov] 
520 3 |a Blood levels of vascular endothelial growth factor, the main marker of angiogenesis activity, and coagulation hemostasis were studied in CDF1 mice with transplanted P-388 lymphocytic leukemia. Blood levels of vascular endothelial growth factor increased by 168% in mice with tumors. The animals developed the hypercoagulation syndrome manifesting in shorter activated partial thromboplastin time and prothrombin time and development of hyperfibrinogenemia. 
540 |a Springer Science+Business Media New York, 2015 
690 7 |a tumor  |2 nationallicence 
690 7 |a hemostasis  |2 nationallicence 
690 7 |a neoangiogenesis  |2 nationallicence 
690 7 |a vascular endothelial growth factor  |2 nationallicence 
690 7 |a P-388 leukemia  |2 nationallicence 
700 1 |a Trashkov  |D A.  |u St. Petersburg State Pediatric Medical University, the Ministry of Health of the Russian Federation, St. Petersburg, Russia  |4 aut 
700 1 |a Panchenko  |D A.  |u St. Petersburg State Pediatric Medical University, the Ministry of Health of the Russian Federation, St. Petersburg, Russia  |4 aut 
700 1 |a Kayukova  |D E.  |u St. Petersburg State Pediatric Medical University, the Ministry of Health of the Russian Federation, St. Petersburg, Russia  |4 aut 
700 1 |a Korablev  |D R.  |u St. Petersburg State Pediatric Medical University, the Ministry of Health of the Russian Federation, St. Petersburg, Russia  |4 aut 
700 1 |a Pechatnikova  |D V.  |u St. Petersburg State Pediatric Medical University, the Ministry of Health of the Russian Federation, St. Petersburg, Russia  |4 aut 
700 1 |a Vasil'ev  |D A.  |u St. Petersburg State Pediatric Medical University, the Ministry of Health of the Russian Federation, St. Petersburg, Russia  |4 aut 
700 1 |a Anisimov  |D V.  |u N. N. Petrov Research Institute of Oncology, Ministry of Health of the Russian Federation, St. Petersburg, Russia  |4 aut 
773 0 |t Bulletin of Experimental Biology and Medicine  |d Springer US; http://www.springer-ny.com  |g 158/4(2015-02-01), 497-499  |x 0007-4888  |q 158:4<497  |1 2015  |2 158  |o 10517 
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950 |B NATIONALLICENCE  |P 700  |E 1-  |a Trashkov  |D A.  |u St. Petersburg State Pediatric Medical University, the Ministry of Health of the Russian Federation, St. Petersburg, Russia  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Panchenko  |D A.  |u St. Petersburg State Pediatric Medical University, the Ministry of Health of the Russian Federation, St. Petersburg, Russia  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Kayukova  |D E.  |u St. Petersburg State Pediatric Medical University, the Ministry of Health of the Russian Federation, St. Petersburg, Russia  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Korablev  |D R.  |u St. Petersburg State Pediatric Medical University, the Ministry of Health of the Russian Federation, St. Petersburg, Russia  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Pechatnikova  |D V.  |u St. Petersburg State Pediatric Medical University, the Ministry of Health of the Russian Federation, St. Petersburg, Russia  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Vasil'ev  |D A.  |u St. Petersburg State Pediatric Medical University, the Ministry of Health of the Russian Federation, St. Petersburg, Russia  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Anisimov  |D V.  |u N. N. Petrov Research Institute of Oncology, Ministry of Health of the Russian Federation, St. Petersburg, Russia  |4 aut 
950 |B NATIONALLICENCE  |P 773  |E 0-  |t Bulletin of Experimental Biology and Medicine  |d Springer US; http://www.springer-ny.com  |g 158/4(2015-02-01), 497-499  |x 0007-4888  |q 158:4<497  |1 2015  |2 158  |o 10517