Effects of Immunomodulators on Functional Activity of Innate Immunity Cells Infected with Streptococcus pneumoniae
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| 024 | 7 | 0 | |a 10.1007/s10517-015-2785-0 |2 doi |
| 035 | |a (NATIONALLICENCE)springer-10.1007/s10517-015-2785-0 | ||
| 245 | 0 | 0 | |a Effects of Immunomodulators on Functional Activity of Innate Immunity Cells Infected with Streptococcus pneumoniae |h [Elektronische Daten] |c [N. Plekhova, N. Kondrashova, L. Somova, E. Drobot, I. Lyapun] |
| 520 | 3 | |a Low activity of bactericidal enzymes was found in innate immunity cells infected with S. pneumonia. The death of these cells was fastened under these conditions. On the contrary, treatment with antibiotic maxifloxacin was followed by an increase in activity of bactericidal enzymes in phagocytes and induced their death via necrosis. Analysis of the therapeutic properties of immunomodulators tinrostim and licopid in combination with maxifloxacin showed that these combinations correct functional activity of cells infected with S. pneumonia. | |
| 540 | |a Springer Science+Business Media New York, 2015 | ||
| 690 | 7 | |a innate immunity cells |2 nationallicence | |
| 690 | 7 | |a Streptococcus pneumonia |2 nationallicence | |
| 690 | 7 | |a immunomodulators |2 nationallicence | |
| 690 | 7 | |a antibiotics |2 nationallicence | |
| 690 | 7 | |a Apoptosis |2 nationallicence | |
| 700 | 1 | |a Plekhova |D N. |u G. P. Somov Research Institute of Epidemiology and Microbiology, Siberian Division of the Russian Academy of Medical Sciences, Vladivostok, Russia |4 aut | |
| 700 | 1 | |a Kondrashova |D N. |u G. P. Somov Research Institute of Epidemiology and Microbiology, Siberian Division of the Russian Academy of Medical Sciences, Vladivostok, Russia |4 aut | |
| 700 | 1 | |a Somova |D L. |u G. P. Somov Research Institute of Epidemiology and Microbiology, Siberian Division of the Russian Academy of Medical Sciences, Vladivostok, Russia |4 aut | |
| 700 | 1 | |a Drobot |D E. |u G. P. Somov Research Institute of Epidemiology and Microbiology, Siberian Division of the Russian Academy of Medical Sciences, Vladivostok, Russia |4 aut | |
| 700 | 1 | |a Lyapun |D I. |u G. P. Somov Research Institute of Epidemiology and Microbiology, Siberian Division of the Russian Academy of Medical Sciences, Vladivostok, Russia |4 aut | |
| 773 | 0 | |t Bulletin of Experimental Biology and Medicine |d Springer US; http://www.springer-ny.com |g 158/4(2015-02-01), 461-464 |x 0007-4888 |q 158:4<461 |1 2015 |2 158 |o 10517 | |
| 856 | 4 | 0 | |u https://doi.org/10.1007/s10517-015-2785-0 |q text/html |z Onlinezugriff via DOI |
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| 908 | |D 1 |a research-article |2 jats | ||
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| 950 | |B NATIONALLICENCE |P 856 |E 40 |u https://doi.org/10.1007/s10517-015-2785-0 |q text/html |z Onlinezugriff via DOI | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Plekhova |D N. |u G. P. Somov Research Institute of Epidemiology and Microbiology, Siberian Division of the Russian Academy of Medical Sciences, Vladivostok, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Kondrashova |D N. |u G. P. Somov Research Institute of Epidemiology and Microbiology, Siberian Division of the Russian Academy of Medical Sciences, Vladivostok, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Somova |D L. |u G. P. Somov Research Institute of Epidemiology and Microbiology, Siberian Division of the Russian Academy of Medical Sciences, Vladivostok, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Drobot |D E. |u G. P. Somov Research Institute of Epidemiology and Microbiology, Siberian Division of the Russian Academy of Medical Sciences, Vladivostok, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Lyapun |D I. |u G. P. Somov Research Institute of Epidemiology and Microbiology, Siberian Division of the Russian Academy of Medical Sciences, Vladivostok, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 773 |E 0- |t Bulletin of Experimental Biology and Medicine |d Springer US; http://www.springer-ny.com |g 158/4(2015-02-01), 461-464 |x 0007-4888 |q 158:4<461 |1 2015 |2 158 |o 10517 | ||