Isolation and Culturing of Trophoblasts from Human Terminal Placenta

Verfasser / Beitragende:
[T. Kolokol'tsova, N. Saburina, P. Poltavtseva, G. Sukhikh]
Ort, Verlag, Jahr:
2015
Enthalten in:
Bulletin of Experimental Biology and Medicine, 158/4(2015-02-01), 532-536
Format:
Artikel (online)
ID: 605538204
LEADER caa a22 4500
001 605538204
003 CHVBK
005 20210128100901.0
007 cr unu---uuuuu
008 210128e20150201xx s 000 0 eng
024 7 0 |a 10.1007/s10517-015-2802-3  |2 doi 
035 |a (NATIONALLICENCE)springer-10.1007/s10517-015-2802-3 
245 0 0 |a Isolation and Culturing of Trophoblasts from Human Terminal Placenta  |h [Elektronische Daten]  |c [T. Kolokol'tsova, N. Saburina, P. Poltavtseva, G. Sukhikh] 
520 3 |a Trophoblast culture was derived from the islets of cell migrating from the fragments of placental microvilli. The isolated cells retained their cytotrophoblast phenotype longer (until passage 2-3) and then gained characteristics of proliferating mesenchymal cells. We conclude that changes in the morphology and co-expression of epithelial (cytokeratin 7) and mesenchymal (vimentin) markers attest to epithelial mesenchymal transition. 
540 |a Springer Science+Business Media New York, 2015 
690 7 |a trophoblast  |2 nationallicence 
690 7 |a placenta  |2 nationallicence 
690 7 |a trophoblast culture  |2 nationallicence 
690 7 |a isolation of trophoblasts  |2 nationallicence 
690 7 |a cytokeratin 7  |2 nationallicence 
700 1 |a Kolokol'tsova  |D T.  |u Research Institute of General Pathology and Pathophysiology, Russian Academy of Medical Sciences, Moscow, Russia  |4 aut 
700 1 |a Saburina  |D N.  |u Research Institute of General Pathology and Pathophysiology, Russian Academy of Medical Sciences, Moscow, Russia  |4 aut 
700 1 |a Poltavtseva  |D P.  |u V. I. Kulakov Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of the Russian Federation, Moscow, Russia  |4 aut 
700 1 |a Sukhikh  |D G.  |u Research Institute of General Pathology and Pathophysiology, Russian Academy of Medical Sciences, Moscow, Russia  |4 aut 
773 0 |t Bulletin of Experimental Biology and Medicine  |d Springer US; http://www.springer-ny.com  |g 158/4(2015-02-01), 532-536  |x 0007-4888  |q 158:4<532  |1 2015  |2 158  |o 10517 
856 4 0 |u https://doi.org/10.1007/s10517-015-2802-3  |q text/html  |z Onlinezugriff via DOI 
898 |a BK010053  |b XK010053  |c XK010000 
900 7 |a Metadata rights reserved  |b Springer special CC-BY-NC licence  |2 nationallicence 
908 |D 1  |a research-article  |2 jats 
949 |B NATIONALLICENCE  |F NATIONALLICENCE  |b NL-springer 
950 |B NATIONALLICENCE  |P 856  |E 40  |u https://doi.org/10.1007/s10517-015-2802-3  |q text/html  |z Onlinezugriff via DOI 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Kolokol'tsova  |D T.  |u Research Institute of General Pathology and Pathophysiology, Russian Academy of Medical Sciences, Moscow, Russia  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Saburina  |D N.  |u Research Institute of General Pathology and Pathophysiology, Russian Academy of Medical Sciences, Moscow, Russia  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Poltavtseva  |D P.  |u V. I. Kulakov Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of the Russian Federation, Moscow, Russia  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Sukhikh  |D G.  |u Research Institute of General Pathology and Pathophysiology, Russian Academy of Medical Sciences, Moscow, Russia  |4 aut 
950 |B NATIONALLICENCE  |P 773  |E 0-  |t Bulletin of Experimental Biology and Medicine  |d Springer US; http://www.springer-ny.com  |g 158/4(2015-02-01), 532-536  |x 0007-4888  |q 158:4<532  |1 2015  |2 158  |o 10517