The Use of Automated System for EEG Analysis and Feedback Cerebral Stimulation to Stop Epileptiform Activity in WAG/Rij Rats

Verfasser / Beitragende:
[V. Blik, A. Aristov, N. Chepurnova]
Ort, Verlag, Jahr:
2015
Enthalten in:
Bulletin of Experimental Biology and Medicine, 158/4(2015-02-01), 520-522
Format:
Artikel (online)
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024 7 0 |a 10.1007/s10517-015-2799-7  |2 doi 
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245 0 4 |a The Use of Automated System for EEG Analysis and Feedback Cerebral Stimulation to Stop Epileptiform Activity in WAG/Rij Rats  |h [Elektronische Daten]  |c [V. Blik, A. Aristov, N. Chepurnova] 
520 3 |a Original software program is described, which revealed EEG activity characteristic of the onset of epileptic seizure and turned on electrical stimulation of the nucleus basalis of Meynert in WAG/Rij rats with congenital absence epilepsy. The program reliably detected the onset of seizure and automatically stopped it with a high-frequency train of electrical impulses (100-150 Hz). Thus, a feedback system of deep brain stimulation has been developed to stop early manifestations of absence epileptiform seizures. The study can be a base to develop an implanted apparatus to automatically analyze EEG and stimulate the brain to stop the epileptic seizures. 
540 |a Springer Science+Business Media New York, 2015 
690 7 |a absence epilepsy  |2 nationallicence 
690 7 |a electrical stimulation of the brain  |2 nationallicence 
700 1 |a Blik  |D V.  |u Biological Faculty, M. V. Lomonosov Moscow State University, Moscow, Russia  |4 aut 
700 1 |a Aristov  |D A.  |u Biological Faculty, M. V. Lomonosov Moscow State University, Moscow, Russia  |4 aut 
700 1 |a Chepurnova  |D N.  |u Biological Faculty, M. V. Lomonosov Moscow State University, Moscow, Russia  |4 aut 
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950 |B NATIONALLICENCE  |P 700  |E 1-  |a Blik  |D V.  |u Biological Faculty, M. V. Lomonosov Moscow State University, Moscow, Russia  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Aristov  |D A.  |u Biological Faculty, M. V. Lomonosov Moscow State University, Moscow, Russia  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Chepurnova  |D N.  |u Biological Faculty, M. V. Lomonosov Moscow State University, Moscow, Russia  |4 aut 
950 |B NATIONALLICENCE  |P 773  |E 0-  |t Bulletin of Experimental Biology and Medicine  |d Springer US; http://www.springer-ny.com  |g 158/4(2015-02-01), 520-522  |x 0007-4888  |q 158:4<520  |1 2015  |2 158  |o 10517