caa a22 4500 60553831X CHVBK 20210128100901.0 cr unu---uuuuu 210128e20150201xx s 000 0 eng 10.1007/s10517-015-2799-7 doi (NATIONALLICENCE)springer-10.1007/s10517-015-2799-7 The Use of Automated System for EEG Analysis and Feedback Cerebral Stimulation to Stop Epileptiform Activity in WAG/Rij Rats [Elektronische Daten] [V. Blik, A. Aristov, N. Chepurnova] Original software program is described, which revealed EEG activity characteristic of the onset of epileptic seizure and turned on electrical stimulation of the nucleus basalis of Meynert in WAG/Rij rats with congenital absence epilepsy. The program reliably detected the onset of seizure and automatically stopped it with a high-frequency train of electrical impulses (100-150 Hz). Thus, a feedback system of deep brain stimulation has been developed to stop early manifestations of absence epileptiform seizures. The study can be a base to develop an implanted apparatus to automatically analyze EEG and stimulate the brain to stop the epileptic seizures. Springer Science+Business Media New York, 2015 absence epilepsy nationallicence electrical stimulation of the brain nationallicence Blik V. Biological Faculty, M. V. Lomonosov Moscow State University, Moscow, Russia aut Aristov A. Biological Faculty, M. V. Lomonosov Moscow State University, Moscow, Russia aut Chepurnova N. Biological Faculty, M. V. Lomonosov Moscow State University, Moscow, Russia aut Bulletin of Experimental Biology and Medicine Springer US; http://www.springer-ny.com 158/4(2015-02-01), 520-522 0007-4888 158:4<520 2015 158 10517 https://doi.org/10.1007/s10517-015-2799-7 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s10517-015-2799-7 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Blik V. Biological Faculty, M. V. Lomonosov Moscow State University, Moscow, Russia aut NATIONALLICENCE 700 1- Aristov A. Biological Faculty, M. V. Lomonosov Moscow State University, Moscow, Russia aut NATIONALLICENCE 700 1- Chepurnova N. Biological Faculty, M. V. Lomonosov Moscow State University, Moscow, Russia aut NATIONALLICENCE 773 0- Bulletin of Experimental Biology and Medicine Springer US; http://www.springer-ny.com 158/4(2015-02-01), 520-522 0007-4888 158:4<520 2015 158 10517