Comparative Analysis of the Expression of Surface Markers on Fibroblasts and Fibroblast-Like Cells Isolated from Different Human Tissues
Gespeichert in:
Verfasser / Beitragende:
[A. Lupatov, A. Vdovin, I. Vakhrushev, R. Poltavtseva, K. Yarygin]
Ort, Verlag, Jahr:
2015
Enthalten in:
Bulletin of Experimental Biology and Medicine, 158/4(2015-02-01), 537-543
Format:
Artikel (online)
Online Zugang:
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| 024 | 7 | 0 | |a 10.1007/s10517-015-2803-2 |2 doi |
| 035 | |a (NATIONALLICENCE)springer-10.1007/s10517-015-2803-2 | ||
| 245 | 0 | 0 | |a Comparative Analysis of the Expression of Surface Markers on Fibroblasts and Fibroblast-Like Cells Isolated from Different Human Tissues |h [Elektronische Daten] |c [A. Lupatov, A. Vdovin, I. Vakhrushev, R. Poltavtseva, K. Yarygin] |
| 520 | 3 | |a Expression of 20 surface markers was analyzed in cultures of mesenchymal stromal cells of the umbilical cord, fibroblasts from adult and fetal human skin, and fi broblast-like cells of fetal liver was analyzed by fl ow cytometry. The studied cultures did not express hemopoietic cells markers, but were positive for CD73, CD90, and CD105 markers recommended by the International Society of Cell Therapy for the identifi cation of the multipotent mesenchymal stromal cells. Fetal liver fi broblast-like cells were positive for CD54; this marker was absent in skin fi broblast cultures, but was expressed by umbilical cord mesenchymal stromal cells. Further study of these cells revealed a minor subpopulation of cells co-expressing CD24 and CD90 or CD24 and CD54. We hypothesized that these cells probably participate in epithelial mesenchymal transition. | |
| 540 | |a Springer Science+Business Media New York, 2015 | ||
| 690 | 7 | |a multipotent mesenchymal stromal cells |2 nationallicence | |
| 690 | 7 | |a umbilical cord |2 nationallicence | |
| 690 | 7 | |a fibroblasts |2 nationallicence | |
| 690 | 7 | |a fetal liver |2 nationallicence | |
| 690 | 7 | |a surface markers |2 nationallicence | |
| 700 | 1 | |a Lupatov |D A. |u V. N. Orekhovich Research Institute of Biomedical Chemistry, Moscow, Russia |4 aut | |
| 700 | 1 | |a Vdovin |D A. |u V. N. Orekhovich Research Institute of Biomedical Chemistry, Moscow, Russia |4 aut | |
| 700 | 1 | |a Vakhrushev |D I. |u V. N. Orekhovich Research Institute of Biomedical Chemistry, Moscow, Russia |4 aut | |
| 700 | 1 | |a Poltavtseva |D R. |u V. I. Kulakov Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of the Russian Federation, Moscow, Russia |4 aut | |
| 700 | 1 | |a Yarygin |D K. |u V. N. Orekhovich Research Institute of Biomedical Chemistry, Moscow, Russia |4 aut | |
| 773 | 0 | |t Bulletin of Experimental Biology and Medicine |d Springer US; http://www.springer-ny.com |g 158/4(2015-02-01), 537-543 |x 0007-4888 |q 158:4<537 |1 2015 |2 158 |o 10517 | |
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| 950 | |B NATIONALLICENCE |P 856 |E 40 |u https://doi.org/10.1007/s10517-015-2803-2 |q text/html |z Onlinezugriff via DOI | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Lupatov |D A. |u V. N. Orekhovich Research Institute of Biomedical Chemistry, Moscow, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Vdovin |D A. |u V. N. Orekhovich Research Institute of Biomedical Chemistry, Moscow, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Vakhrushev |D I. |u V. N. Orekhovich Research Institute of Biomedical Chemistry, Moscow, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Poltavtseva |D R. |u V. I. Kulakov Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of the Russian Federation, Moscow, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Yarygin |D K. |u V. N. Orekhovich Research Institute of Biomedical Chemistry, Moscow, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 773 |E 0- |t Bulletin of Experimental Biology and Medicine |d Springer US; http://www.springer-ny.com |g 158/4(2015-02-01), 537-543 |x 0007-4888 |q 158:4<537 |1 2015 |2 158 |o 10517 | ||