Effects of Acoustic and EHF Impulses on Multipotent Stromal Cells during Formation of Bone Marrow Containing Heterotopic Organs in Tissue Engineered Constructions
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| 024 | 7 | 0 | |a 10.1007/s10517-015-2836-6 |2 doi |
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| 245 | 0 | 0 | |a Effects of Acoustic and EHF Impulses on Multipotent Stromal Cells during Formation of Bone Marrow Containing Heterotopic Organs in Tissue Engineered Constructions |h [Elektronische Daten] |c [R. Chaikhalyan, V. Yusupov, Yu. Gorskaya, A. Kuralesova, Yu. Gerasimov, A. Sviridov, A. Tambiev, N. Vorob'eva, A. Shishkova, I. Moskvina, V. Bagratashvili] |
| 520 | 3 | |a We studied the effects of physical factors (acoustic impulses of laser-induced hydrodynamics, AILIH, and EHF-radiation) on the formation of heterotopic bone marrow organs. Suspension of precipitated mouse bone marrow cells was exposed to AILIH and EHF or their combinations (AILIH+EHF, EHF+AILIH). The developed tissue engineering constructions (gelatin sponges containing 107 nucleated bone marrow cells exposed to physical factors) were transplanted under the renal capsule of syngeneic mice. Analysis of newly formed hemopoietic organs was performed after 3 and 5 months. The total amount of hemopoietic cells, number of multipotent stromal cells, efficiency of colony formation from these cells, and weight of bone capsule of the transplants were measured. Microscopic study showed that 5-month transplants were significantly larger than 3-month transplants and contained 3-fold more hemopoietic cells (20-fold in the AILIH+EHF group). The number of multipotent stromal cells was maximum in EHF+AILIH group (by 2.2 times higher than in the control) and minimum in AILIH+EHF group. Exposure to EHF+AILIH had most pronounced effect on the formation of the bone marrow transplants. The weight of bone capsules more rapidly increased in gelatin sponges of 3-month transplants of EHF+AILIH and AILIH groups. These data suggest that the studied physical factors can be used for acceleration of rehabilitation process. | |
| 540 | |a Springer Science+Business Media New York, 2015 | ||
| 690 | 7 | |a organ containing bone marrow |2 nationallicence | |
| 690 | 7 | |a multipotent stromal cells |2 nationallicence | |
| 690 | 7 | |a heterotopic transplantation |2 nationallicence | |
| 690 | 7 | |a EHF-radiation |2 nationallicence | |
| 690 | 7 | |a acoustic impulses |2 nationallicence | |
| 700 | 1 | |a Chaikhalyan |D R. |u N. F. Gamaleya Research Institute of Epidemiology and Microbiology, Ministry of Health of the Russian Federation, Moscow, Russia |4 aut | |
| 700 | 1 | |a Yusupov |D V. |u V. I. Il'ichev Pacific Oceanological Institute, Far-Eastern Division of Russian Academy of Sciences, Vladivostok, Russia |4 aut | |
| 700 | 1 | |a Gorskaya |D Yu |u N. F. Gamaleya Research Institute of Epidemiology and Microbiology, Ministry of Health of the Russian Federation, Moscow, Russia |4 aut | |
| 700 | 1 | |a Kuralesova |D A. |u N. F. Gamaleya Research Institute of Epidemiology and Microbiology, Ministry of Health of the Russian Federation, Moscow, Russia |4 aut | |
| 700 | 1 | |a Gerasimov |D Yu |u N. F. Gamaleya Research Institute of Epidemiology and Microbiology, Ministry of Health of the Russian Federation, Moscow, Russia |4 aut | |
| 700 | 1 | |a Sviridov |D A. |u Institute on Laser and Information Technologies, Russian Academy of Sciences, Moscow, Russia |4 aut | |
| 700 | 1 | |a Tambiev |D A. |u Biological Faculty of M. V. Lomonosov Moscow State University, Moscow, Russia |4 aut | |
| 700 | 1 | |a Vorob'eva |D N. |u Institute on Laser and Information Technologies, Russian Academy of Sciences, Moscow, Russia |4 aut | |
| 700 | 1 | |a Shishkova |D A. |u N. F. Gamaleya Research Institute of Epidemiology and Microbiology, Ministry of Health of the Russian Federation, Moscow, Russia |4 aut | |
| 700 | 1 | |a Moskvina |D I. |u N. F. Gamaleya Research Institute of Epidemiology and Microbiology, Ministry of Health of the Russian Federation, Moscow, Russia |4 aut | |
| 700 | 1 | |a Bagratashvili |D V. |u Institute on Laser and Information Technologies, Russian Academy of Sciences, Moscow, Russia |4 aut | |
| 773 | 0 | |t Bulletin of Experimental Biology and Medicine |d Springer US; http://www.springer-ny.com |g 158/5(2015-03-01), 688-691 |x 0007-4888 |q 158:5<688 |1 2015 |2 158 |o 10517 | |
| 856 | 4 | 0 | |u https://doi.org/10.1007/s10517-015-2836-6 |q text/html |z Onlinezugriff via DOI |
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| 900 | 7 | |a Metadata rights reserved |b Springer special CC-BY-NC licence |2 nationallicence | |
| 908 | |D 1 |a research-article |2 jats | ||
| 949 | |B NATIONALLICENCE |F NATIONALLICENCE |b NL-springer | ||
| 950 | |B NATIONALLICENCE |P 856 |E 40 |u https://doi.org/10.1007/s10517-015-2836-6 |q text/html |z Onlinezugriff via DOI | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Chaikhalyan |D R. |u N. F. Gamaleya Research Institute of Epidemiology and Microbiology, Ministry of Health of the Russian Federation, Moscow, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Yusupov |D V. |u V. I. Il'ichev Pacific Oceanological Institute, Far-Eastern Division of Russian Academy of Sciences, Vladivostok, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Gorskaya |D Yu |u N. F. Gamaleya Research Institute of Epidemiology and Microbiology, Ministry of Health of the Russian Federation, Moscow, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Kuralesova |D A. |u N. F. Gamaleya Research Institute of Epidemiology and Microbiology, Ministry of Health of the Russian Federation, Moscow, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Gerasimov |D Yu |u N. F. Gamaleya Research Institute of Epidemiology and Microbiology, Ministry of Health of the Russian Federation, Moscow, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Sviridov |D A. |u Institute on Laser and Information Technologies, Russian Academy of Sciences, Moscow, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Tambiev |D A. |u Biological Faculty of M. V. Lomonosov Moscow State University, Moscow, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Vorob'eva |D N. |u Institute on Laser and Information Technologies, Russian Academy of Sciences, Moscow, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Shishkova |D A. |u N. F. Gamaleya Research Institute of Epidemiology and Microbiology, Ministry of Health of the Russian Federation, Moscow, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Moskvina |D I. |u N. F. Gamaleya Research Institute of Epidemiology and Microbiology, Ministry of Health of the Russian Federation, Moscow, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Bagratashvili |D V. |u Institute on Laser and Information Technologies, Russian Academy of Sciences, Moscow, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 773 |E 0- |t Bulletin of Experimental Biology and Medicine |d Springer US; http://www.springer-ny.com |g 158/5(2015-03-01), 688-691 |x 0007-4888 |q 158:5<688 |1 2015 |2 158 |o 10517 | ||