Transformation of Catalytic Characteristics of Cerebral Monoamine Oxidases in Experimental Posttraumatic Stress Disorders
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| 024 | 7 | 0 | |a 10.1007/s10517-015-2826-8 |2 doi |
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| 245 | 0 | 0 | |a Transformation of Catalytic Characteristics of Cerebral Monoamine Oxidases in Experimental Posttraumatic Stress Disorders |h [Elektronische Daten] |c [L. Kolesnikova, A. Popova, R. Deev, A. Sinitskii, L. Krupitskaya] |
| 520 | 3 | |a We studied the contribution of the transformation of the catalytic properties of cerebral monoamine oxidase in the development of behavioral disorders during stress. Monoamine oxidase activities and catalytic characteristics, LPO intensity, and oxidative modification of proteins in suspension of the brain mitochondria were evaluated over the course of experimental posttraumatic stress disorder. The detected shifts were comparable with the results of neuroethologic testing. The development of behavioral disorders presented by low exploratory activity and high anxiety was associated with transformation of catalytic characteristics of cerebral monoamine oxidases, associated with the development of oxidative stress with predominant intensification of metal-catalyzed protein oxidation. | |
| 540 | |a Springer Science+Business Media New York, 2015 | ||
| 690 | 7 | |a monoamine oxidase |2 nationallicence | |
| 690 | 7 | |a posttraumatic stress disorder |2 nationallicence | |
| 690 | 7 | |a free radical oxidation |2 nationallicence | |
| 700 | 1 | |a Kolesnikova |D L. |u Research Center of Family Health and Human Reproduction Problems, Siberian Division of the Russian Academy of Medical Sciences, Irkutsk, Russia |4 aut | |
| 700 | 1 | |a Popova |D A. |u Research Center of Family Health and Human Reproduction Problems, Siberian Division of the Russian Academy of Medical Sciences, Irkutsk, Russia |4 aut | |
| 700 | 1 | |a Deev |D R. |u South-Ural State Medical University, Ministry of Health of the Russian Federation, Chelyabinsk, Russia |4 aut | |
| 700 | 1 | |a Sinitskii |D A. |u South-Ural State Medical University, Ministry of Health of the Russian Federation, Chelyabinsk, Russia |4 aut | |
| 700 | 1 | |a Krupitskaya |D L. |u Research Center of Family Health and Human Reproduction Problems, Siberian Division of the Russian Academy of Medical Sciences, Irkutsk, Russia |4 aut | |
| 773 | 0 | |t Bulletin of Experimental Biology and Medicine |d Springer US; http://www.springer-ny.com |g 158/5(2015-03-01), 641-643 |x 0007-4888 |q 158:5<641 |1 2015 |2 158 |o 10517 | |
| 856 | 4 | 0 | |u https://doi.org/10.1007/s10517-015-2826-8 |q text/html |z Onlinezugriff via DOI |
| 898 | |a BK010053 |b XK010053 |c XK010000 | ||
| 900 | 7 | |a Metadata rights reserved |b Springer special CC-BY-NC licence |2 nationallicence | |
| 908 | |D 1 |a research-article |2 jats | ||
| 949 | |B NATIONALLICENCE |F NATIONALLICENCE |b NL-springer | ||
| 950 | |B NATIONALLICENCE |P 856 |E 40 |u https://doi.org/10.1007/s10517-015-2826-8 |q text/html |z Onlinezugriff via DOI | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Kolesnikova |D L. |u Research Center of Family Health and Human Reproduction Problems, Siberian Division of the Russian Academy of Medical Sciences, Irkutsk, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Popova |D A. |u Research Center of Family Health and Human Reproduction Problems, Siberian Division of the Russian Academy of Medical Sciences, Irkutsk, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Deev |D R. |u South-Ural State Medical University, Ministry of Health of the Russian Federation, Chelyabinsk, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Sinitskii |D A. |u South-Ural State Medical University, Ministry of Health of the Russian Federation, Chelyabinsk, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Krupitskaya |D L. |u Research Center of Family Health and Human Reproduction Problems, Siberian Division of the Russian Academy of Medical Sciences, Irkutsk, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 773 |E 0- |t Bulletin of Experimental Biology and Medicine |d Springer US; http://www.springer-ny.com |g 158/5(2015-03-01), 641-643 |x 0007-4888 |q 158:5<641 |1 2015 |2 158 |o 10517 | ||