Evaluation of Fibrogenic Potential of Industrial Multi-Walled Carbon Nanotubes in Acute Aspiration Experiment
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| 024 | 7 | 0 | |a 10.1007/s10517-015-2835-7 |2 doi |
| 035 | |a (NATIONALLICENCE)springer-10.1007/s10517-015-2835-7 | ||
| 245 | 0 | 0 | |a Evaluation of Fibrogenic Potential of Industrial Multi-Walled Carbon Nanotubes in Acute Aspiration Experiment |h [Elektronische Daten] |c [T. Khaliullin, A. Shvedova, E. Kisin, R. Zalyalov, L. Fatkhutdinova] |
| 520 | 3 | |a Local inflammatory response in the lungs and fi brogenic potential of multi-walled carbon nanotubes were studied in an acute aspiration experiment in mice. The doses were chosen based on the concentration of nanotubes in the air at a workplace of the company-producer. ELISA, fl ow cytometry, enhanced darkfield microscopy, and histological examination showed that multi-walled carbon nanotubes induced local inflammation, oxidative stress, and connective tissue growth (fibrosis). Serum levels of TGF-β1 and osteopontin proteins can serve as potential exposure biomarkers. | |
| 540 | |a Springer Science+Business Media New York, 2015 | ||
| 690 | 7 | |a carbon nanotubes |2 nationallicence | |
| 690 | 7 | |a in vivo |2 nationallicence | |
| 690 | 7 | |a fibrosis |2 nationallicence | |
| 690 | 7 | |a bronchoalveolar lavage |2 nationallicence | |
| 700 | 1 | |a Khaliullin |D T. |u Kazan State Medical University, Kazan, Russia |4 aut | |
| 700 | 1 | |a Shvedova |D A. |u National Institute for Occupational Safety and Health, Morgantown, USA |4 aut | |
| 700 | 1 | |a Kisin |D E. |u National Institute for Occupational Safety and Health, Morgantown, USA |4 aut | |
| 700 | 1 | |a Zalyalov |D R. |u Kazan State Medical University, Kazan, Russia |4 aut | |
| 700 | 1 | |a Fatkhutdinova |D L. |u Kazan State Medical University, Kazan, Russia |4 aut | |
| 773 | 0 | |t Bulletin of Experimental Biology and Medicine |d Springer US; http://www.springer-ny.com |g 158/5(2015-03-01), 684-687 |x 0007-4888 |q 158:5<684 |1 2015 |2 158 |o 10517 | |
| 856 | 4 | 0 | |u https://doi.org/10.1007/s10517-015-2835-7 |q text/html |z Onlinezugriff via DOI |
| 898 | |a BK010053 |b XK010053 |c XK010000 | ||
| 900 | 7 | |a Metadata rights reserved |b Springer special CC-BY-NC licence |2 nationallicence | |
| 908 | |D 1 |a research-article |2 jats | ||
| 949 | |B NATIONALLICENCE |F NATIONALLICENCE |b NL-springer | ||
| 950 | |B NATIONALLICENCE |P 856 |E 40 |u https://doi.org/10.1007/s10517-015-2835-7 |q text/html |z Onlinezugriff via DOI | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Khaliullin |D T. |u Kazan State Medical University, Kazan, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Shvedova |D A. |u National Institute for Occupational Safety and Health, Morgantown, USA |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Kisin |D E. |u National Institute for Occupational Safety and Health, Morgantown, USA |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Zalyalov |D R. |u Kazan State Medical University, Kazan, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Fatkhutdinova |D L. |u Kazan State Medical University, Kazan, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 773 |E 0- |t Bulletin of Experimental Biology and Medicine |d Springer US; http://www.springer-ny.com |g 158/5(2015-03-01), 684-687 |x 0007-4888 |q 158:5<684 |1 2015 |2 158 |o 10517 | ||